Detailed information of TA system TA020067

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 1533875..1534401
• Replicon: chromosome
• Accession: HG738867
• Organism: Escherichia coli str. K-12 substr. MC4100

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BN896_1382
• Protein ID: CDJ71963.1
• Coordinates: 1533875..1534162 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BN896_1383
• Protein ID: CDJ71964.1
• Coordinates: 1534162..1534401 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BN896_1375	1528899..1529114	-	216	CDJ71956.1	Qin prophage; putative S lysis protein	-
BN896_1376	1529868..1530083	-	216	CDJ71957.1	Qin prophage; cold shock protein	-
BN896_1377	1530384..1530596	+	213	CDJ71958.1	Qin prophage; cold shock protein	-
BN896_1378	1531018..1531770	-	753	CDJ71959.1	Qin prophage; putative antitermination protein Q	-
BN896_1379	1531784..1532731	-	948	CDJ71960.1	Qin prophage protein	-
BN896_1380	1533180..1533431	-	252	CDJ71961.1	Qin prophage protein	-
BN896_1381	1533648..1533803	-	156	CDJ71962.1	Qin prophage; small toxic polypeptide	-
BN896_1382	1533875..1534162	-	288	CDJ71963.1	Qin prophage; toxin of the RelE-RelB toxin-antitoxin system	Toxin
BN896_1383	1534162..1534401	-	240	CDJ71964.1	bifunctional antitoxin/transcriptional repressor RelB	Antitoxin
BN896_1384	1534426..1534731	+	306	CDJ71965.1	Qin prophage protein	-
BN896_1385	1534934..1535266	+	333	CDJ71966.1	Qin prophage protein	-
BN896_1386	1535651..1535878	-	228	CDJ71967.1	Qin prophage protein	-
BN896_1387	1535875..1536165	-	291	CDJ71968.1	Qin prophage protein	-
BN896_1388	1536149..1536379	-	231	CDJ71969.1	DNA-binding transcriptional regulator DicC	-
BN896_1389	1536463..1536870	+	408	CDJ71970.1	transcriptional repressor DicA	-
BN896_1390	1537037..1537192	+	156	CDJ71971.1	Qin prophage protein	-
BN896_1391	1537194..1537322	+	129	CDJ71972.1	Qin prophage protein	-
BN896_1392	1538138..1538326	+	189	CDJ71973.1	Qin prophage; cell division inhibition protein	-
BN896_1393	1538323..1538514	+	192	CDJ71974.1	Qin prophage protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_000913 Escherichia coli str. K-12 substr. MG1655 Prophage TA001041 1631002..1664463 0 View NC_012759 Escherichia coli BW2952 Prophage TA023854 1521085..1554546 0 View NZ_CP009273 Escherichia coli BW25113 Prophage TA048683 1625259..1658720 0 View NC_010473 Escherichia coli str. K-12 substr. DH10B Prophage TA022686 1718651..1753448 0 View NZ_HG738867 Escherichia coli str. K-12 substr. MC4100 strain K-12 Prophage TA285017 1519531..1552992 0 View NC_017625 Escherichia coli DH1 Prophage TA027170 2221734..2249263 0.009 View NZ_AP021946 Escherichia coli strain WP2-S18-ESBL-08 Prophage TA033893 2451962..2495155 0.008 View NZ_CP010439 Escherichia coli K-12 strain K-12 MG1655 Prophage TA052469 2371482..2397224 0.008 View NZ_CP010441 Escherichia coli K-12 strain K-12 MG1655 Prophage TA052548 2374573..2408034 0 View NZ_CP011113 Escherichia coli strain RR1 Prophage TA053405 1593305..1621509 0.007 View NZ_CP011124 Escherichia coli strain USML2 Prophage TA053503 3209613..3249971 0.004 View NZ_CP012127 Escherichia coli strain DH1Ec169 Prophage TA055926 1610572..1644033 0 View NZ_CP012868 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA057308 2977202..3010663 0 View NZ_CP012869 Escherichia coli strain K-12 substr. MG1655_TMP32XR1 Prophage TA057339 2977209..3010670 0 View NZ_CP012870 Escherichia coli strain K-12 substr. MG1655_TMP32XR2 Prophage TA057370 2977209..3010670 0 View NZ_CP013952 Escherichia coli strain HST04 Prophage TA059671 4226718..4253586 0.006 View NZ_CP014225 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA060414 4469926..4503387 0 View NZ_CP014348 Escherichia coli str. K-12 substr. MG1655 strain JW5437-1 Prophage TA060779 3669648..3710006 0.004 View NZ_CP018801 Escherichia coli strain tolC- Prophage TA070553 2221021..2255818 0 View NZ_CP019629 Escherichia coli strain MGY Prophage TA073076 1631002..1664463 0 View NZ_CP025268 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA089996 1635821..1669281 0 View NZ_CP026342 Escherichia coli strain 9FA Prophage TA093861 1631002..1657870 0.006 View NZ_CP026343 Escherichia coli strain 9A Prophage TA093904 1631001..1664462 0 View NZ_CP026344 Escherichia coli strain 8FA Prophage TA093947 1631002..1664463 0 View NZ_CP026345 Escherichia coli strain 8A Prophage TA093990 1629453..1657870 0.008 View NZ_CP026346 Escherichia coli strain 7FA Prophage TA094033 1631002..1657870 0.006 View NZ_CP026347 Escherichia coli strain 7A Prophage TA094076 1631002..1664463 0 View NZ_CP026348 Escherichia coli strain 6FA Prophage TA094119 1631002..1664463 0 View NZ_CP026349 Escherichia coli strain 6A Prophage TA094162 1631002..1664463 0 View NZ_CP026350 Escherichia coli strain 5FA Prophage TA094205 1631002..1664463 0 View NZ_CP026351 Escherichia coli strain 5A Prophage TA094248 1631002..1657870 0.006 View NZ_CP026352 Escherichia coli strain 4FA Prophage TA094291 1631002..1657870 0.006 View NZ_CP026354 Escherichia coli strain 3FA Prophage TA094377 1629215..1656744 0.009 View NZ_CP026355 Escherichia coli strain 3A Prophage TA094420 1631002..1664463 0 View NZ_CP026356 Escherichia coli strain 2FA Prophage TA094463 1631002..1664463 0 View NZ_CP026357 Escherichia coli strain 2F_0 Prophage TA094506 1631002..1664463 0 View NZ_CP026358 Escherichia coli strain 2A Prophage TA094549 1631002..1657870 0.006 View NZ_CP026359 Escherichia coli strain 2_0 Prophage TA094592 1631002..1664463 0 View NZ_CP026360 Escherichia coli strain 1FA Prophage TA094635 1631002..1664463 0 View NZ_CP026361 Escherichia coli strain 1A Prophage TA094678 1631002..1664463 0 View NZ_CP029238 Escherichia coli strain CJ236 Prophage TA105250 1631002..1664463 0 View NZ_CP030240 Escherichia coli strain ER1709 Prophage TA107391 3759929..3794723 0 View NZ_CP031214 Escherichia coli strain C600 Prophage TA108583 2258054..2298412 0.004 View NZ_CP032667 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA112075 2218134..2258492 0.004 View NZ_CP032679 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA112107 1631007..1664468 0 View NZ_CP034595 Escherichia coli strain WCHEC035053S1G0 Prophage TA116275 2080640..2114101 0 View NZ_CP037857 Escherichia coli BW25113 strain AM187 Prophage TA120213 1624921..1658382 0 View NZ_CP038857 Escherichia coli strain PigCaeca_2 Prophage TA123269 2238467..2279604 0.01 View NZ_CP040643 Escherichia coli strain BE104 Prophage TA126265 1764966..1798427 0 View NZ_CP040663 Escherichia coli strain EK2009 Prophage TA126352 1619919..1653380 0 View NZ_CP040667 Escherichia coli strain S17-1 Prophage TA126454 1751269..1784730 0 View NZ_CP042843 Escherichia coli strain JME67 Prophage TA136091 2340491..2373952 0 View NZ_CP042845 Escherichia coli strain JME65 Prophage TA136177 2335378..2368839 0 View NZ_CP042846 Escherichia coli strain JME64 Prophage TA136220 2330497..2363958 0 View NZ_CP042865 Escherichia coli strain ATCC BAA-196 Prophage TA136307 2229091..2255959 0.006 View NZ_CP042867 Escherichia coli strain ATCC BAA-196 Prophage TA136338 2228999..2255867 0.006 View NZ_CP043183 Escherichia coli O16:H48 strain PG20180172 Prophage TA137410 2220212..2253673 0 View NZ_CP043185 Escherichia coli O16:H48 strain PG20180171 Prophage TA137428 360597..386339 0.008 View NZ_CP043187 Escherichia coli O16:H48 strain PG20180170 Prophage TA137478 2220208..2253669 0 View NZ_CP043189 Escherichia coli O16:H48 strain PG20180175 Prophage TA137509 2220211..2253672 0 View NZ_CP043191 Escherichia coli O16:H48 strain PG20180173 Prophage TA137541 2220211..2253672 0 View NZ_CP043193 Escherichia coli O16:H48 strain PG20180063 Prophage TA137571 2226806..2253674 0.007 View NZ_CP043195 Escherichia coli O16:H48 strain PG20180062 Prophage TA137602 2508272..2548630 0.004 View NZ_CP043197 Escherichia coli O16:H48 strain PG20180061 Prophage TA137642 4199959..4240317 0.004 View NZ_CP043201 Escherichia coli O16:H48 strain PG20180059 Prophage TA137711 2220211..2253672 0 View NZ_CP043203 Escherichia coli O16:H48 strain PG20180058 Prophage TA137744 2220211..2253672 0 View NZ_CP043205 Escherichia coli O16:H48 strain PG20180054 Prophage TA137777 2227930..2253672 0.008 View NZ_CP043207 Escherichia coli O16:H48 strain PG20180053 Prophage TA137810 2220211..2253672 0 View NZ_CP043209 Escherichia coli O16:H48 strain PG20180052 Prophage TA137843 2220211..2253672 0 View NZ_CP045741 Escherichia coli strain DH5alpha Prophage TA142456 3271084..3299468 0.01 View NZ_CP047127 Escherichia coli K-12 Prophage TA145467 4091062..4119454 0.01 View NZ_CP047594 Escherichia coli strain LD27-1 Prophage TA146827 2235900..2267399 0.008 View NZ_CP053603 Escherichia coli strain Dam/Dcm Prophage TA157065 1615047..1641915 0.006 View NZ_CP054665 Escherichia coli strain IGC_EcoliInv_1.1 Prophage TA160046 1635819..1661561 0.008 View NZ_CP062239 Escherichia coli strain AML001_ev03 Prophage TA173646 1625259..1658720 0 View NZ_CP062240 Escherichia coli strain AML001_ev02 Prophage TA173689 1622609..1651001 0.01 View NZ_CP062241 Escherichia coli strain AML001_ev01 Prophage TA173732 1625259..1658720 0 View NZ_CP062242 Escherichia coli strain AML001_par Prophage TA173775 1625259..1652127 0.006 View NZ_CP062243 Escherichia coli strain AML003_ev03 Prophage TA173818 1625259..1658720 0 View NZ_CP062244 Escherichia coli strain AML003_ev02 Prophage TA173861 1625259..1658720 0 View NZ_CP062245 Escherichia coli strain AML003_ev01 Prophage TA173904 1625258..1658719 0 View NZ_CP062246 Escherichia coli strain AML003_par Prophage TA173947 1625259..1658720 0 View NZ_CP062248 Escherichia coli strain AML002_ev02 Prophage TA174033 1625260..1652128 0.006 View NZ_CP062250 Escherichia coli strain AML002_par Prophage TA174119 1625259..1658720 0 View NZ_CP064678 Escherichia coli K-12 strain CETR3G40 Prophage TA181427 1625259..1658720 0 View NZ_CP064679 Escherichia coli K-12 strain CETR2G40 Prophage TA181470 1625259..1652127 0.006 View NZ_CP064680 Escherichia coli K-12 strain CETR1G40 Prophage TA181513 1625257..1658718 0 View NZ_CP064681 Escherichia coli K-12 strain BZKR3G40 Prophage TA181556 1625259..1652127 0.006 View NZ_CP064682 Escherichia coli K-12 strain BZKR2G40 Prophage TA181599 1625259..1658720 0 View NZ_CP067994 Escherichia coli strain CV601 Prophage TA186401 2221463..2254924 0 View NZ_CP068281 Escherichia coli strain CY706 Prophage TA187058 2874303..2909100 0 View NZ_CP069132 Escherichia coli BW25113 substr. CHXR1G20 Prophage TA189919 1625255..1658716 0 View NZ_CP069133 Escherichia coli BW25113 substr. CHXR2G20 Prophage TA189962 1625259..1658720 0 View NZ_CP069386 Escherichia coli strain XH1815 Prophage TA190295 261320..294781 0 View NZ_CP070962 Escherichia coli strain K-12 J53 Prophage TA194816 1907593..1935799 0.007 View NZ_CP071521 Escherichia coli strain 11202 Prophage TA196524 2215898..2254488 0.004 View NZ_CP072054 Escherichia coli strain K1508 Prophage TA197259 1519531..1552992 0 View NZ_CP075722 Escherichia coli strain CPE35 Prophage TA204324 2222554..2259693 0.008 View NZ_CP076043 Escherichia coli strain Stbl4 Prophage TA204590 1160875..1190368 0.004 View NZ_CP076470 Escherichia coli strain DH5a Prophage TA205746 4079180..4114005 0 View NZ_CP077969 Escherichia coli strain JM83 Prophage TA208757 1549815..1583276 0 View NZ_CP079767 Escherichia coli strain SF10 Prophage TA209975 1067917..1100181 0.009 View NZ_CP079991 Escherichia coli strain KMS2005 Prophage TA210463 2485629..2519090 0 View NZ_CP079992 Escherichia coli strain KMS2001 Prophage TA210495 2485630..2519091 0 View NZ_CP079993 Escherichia coli strain EV36 Prophage TA210527 2485630..2519091 0 View NZ_CP083410 Escherichia coli strain RP437 Prophage TA216371 1630999..1664460 0 View NZ_CP084207 Escherichia coli strain EC2648-R1-1 Prophage TA218255 3031857..3059386 0.009 View NZ_CP084209 Escherichia coli strain EC2648-R2 Prophage TA218286 2222730..2250021 0.009 View NZ_CP084897 Escherichia coli strain gb37 Prophage TA219999 1634347..1660089 0.008 View NZ_CP087136 Escherichia coli strain JW5503 Prophage TA224831 1625806..1652674 0.006 View NZ_CP092037 Escherichia coli strain MG1655-377GD Prophage TA235511 1454974..1491108 0.008 View NZ_CP092702 Escherichia coli strain S-P-C-029.01 Prophage TA236980 1631002..1657870 0.006 View NZ_CP093221 Escherichia coli strain ER2683 Prophage TA237841 3343923..3370791 0.006 View NZ_CP093368 Escherichia coli strain EV36 mutant 1a Prophage TA238251 2485630..2512498 0.006 View NZ_CP097881 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA246421 2218488..2258846 0.004 View NZ_CP097882 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA246447 2211254..2239646 0.01 View NZ_CP097883 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA246473 2211254..2239646 0.01 View NZ_CP097884 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA246500 2828985..2869343 0.004 View NZ_CP099590 Escherichia coli strain WG1 Prophage TA249176 2213004..2249588 0.001 View NZ_CP099590 Escherichia coli strain WG1 Prophage TA249176 2219597..2250451 0.009 View NZ_CP102379 Escherichia coli strain BM28 lysU Prophage TA253541 1503513..1538240 0.001 View NZ_CP102380 Escherichia coli strain BM28 Prophage TA253575 1503513..1538240 0.001 View NZ_CP104326 Escherichia coli strain THB42-F1 Prophage TA257599 2221107..2254568 0 View NZ_CP106994 Escherichia coli strain SY22A6 Prophage TA260129 2226870..2268564 0.005 View NZ_CP106995 Escherichia coli strain SY22B3 Prophage TA260152 2226870..2268564 0.005 View NZ_CP106996 Escherichia coli strain SY22D8 Prophage TA260175 2226870..2268564 0.005 View NZ_CP106997 Escherichia coli strain SY22B6 Prophage TA260198 2226870..2268564 0.005 View NZ_CP106998 Escherichia coli strain SY221 Prophage TA260221 2226870..2268564 0.005 View NZ_CP106999 Escherichia coli strain SY22A4 Prophage TA260244 2226870..2268564 0.005 View NZ_CP107000 Escherichia coli strain SY22B2 Prophage TA260267 2226870..2268564 0.005 View NZ_CP107001 Escherichia coli strain SY22B5 Prophage TA260290 2226870..2268564 0.005 View NZ_CP107002 Escherichia coli strain SY22C3 Prophage TA260313 2226870..2268564 0.005 View NZ_CP107003 Escherichia coli strain SY22B1 Prophage TA260336 2226870..2268564 0.005 View NZ_CP107004 Escherichia coli strain SY22A3 Prophage TA260359 2226870..2268564 0.005 View NZ_CP107005 Escherichia coli strain SY22A1 Prophage TA260382 2226870..2268564 0.005 View NZ_CP110014 Escherichia coli strain HE_100-10 Prophage TA262641 1718639..1753436 0 View NZ_CP110015 Escherichia coli strain HE_150 Prophage TA262667 1718642..1753439 0 View NZ_CP110016 Escherichia coli strain HE_100 Prophage TA262693 1718643..1753440 0 View NZ_CP110017 Escherichia coli strain HE_50 Prophage TA262719 1718642..1753439 0 View NZ_CP110018 Escherichia coli strain DH10B Prophage TA262745 1718651..1753448 0 View NZ_CP110999 Escherichia coli strain J53-p133 Prophage TA264727 2077964..2118322 0.004 View NZ_CP111004 Escherichia coli strain J53-p131 Prophage TA264756 2077964..2118322 0.004 View NZ_CP111008 Escherichia coli strain J53-p130 Prophage TA264784 2077738..2111199 0 View NZ_CP114891 Escherichia coli strain CM2 Prophage TA266905 1702179..1739626 0.002 View NZ_CP114892 Escherichia coli strain CM5 Prophage TA266920 849012..883809 0 View NZ_CP114893 Escherichia coli strain CM13 Prophage TA266961 3451022..3485819 0 View NZ_CP117971 Escherichia coli strain B-1109 Prophage TA272600 2577962..2618799 0.008 View NZ_CP122316 Escherichia coli strain HT-946 Prophage TA276667 1216837..1250298 0 View NZ_CP122318 Escherichia coli strain HT873X1 Prophage TA276729 1250251..1283712 0 View NZ_CP128218 Escherichia coli strain TG1 Prophage TA284417 1253353..1288790 0.002 View NZ_LM995446 Escherichia coli strain K-12 substr. RV308 Prophage TA285435 1579899..1613360 0 View NZ_LN832404 Escherichia coli K-12 substr. AG100 Prophage TA285657 1634656..1668117 0 View NZ_LR881938 Escherichia coli str. K-12 substr. MG1655 strain K-12 Prophage TA289514 1615271..1648732 0 View NZ_LR882052 Escherichia coli isolate 2015-01-466 Prophage TA289589 2200582..2239192 0.006 View NZ_LT615377 Escherichia coli isolate 106 Prophage TA293343 1634656..1668117 0 View NZ_LT615378 Escherichia coli isolate 103 Prophage TA293374 1634656..1661524 0.007 View NZ_LT615378 Escherichia coli isolate 103 Prophage TA293374 1634656..1668117 0 View NC_000913 Escherichia coli str. K-12 substr. MG1655 Prophage TA001041 1631002..1664463 0 View NC_010473 Escherichia coli str. K-12 substr. DH10B Prophage TA022686 1718651..1753448 0 View NC_012759 Escherichia coli BW2952 Prophage TA023854 1521085..1554546 0 View NZ_CP009273 Escherichia coli BW25113 Prophage TA048683 1625259..1658720 0 View NZ_HG738867 Escherichia coli str. K-12 substr. MC4100 strain K-12 Prophage TA285017 1519531..1552992 0	inside	Prophage	-	-	1519531..1552992	33461

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-86)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-79)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11225.22 Da
• Isoelectric Point: 10.1967

>T20067 CDJ71963.1 HG738867:c1534162-1533875 [Escherichia coli str. K-12 substr. MC4100]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL

Nucleotide

• Length: 288 bp

>T20067 HG738867:c1534162-1533875 [Escherichia coli str. K-12 substr. MC4100]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9071.48 Da
• Isoelectric Point: 4.5230

>AT20067 CDJ71964.1 HG738867:c1534401-1534162 [Escherichia coli str. K-12 substr. MC4100]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL

Nucleotide

• Length: 240 bp

>AT20067 HG738867:c1534401-1534162 [Escherichia coli str. K-12 substr. MC4100]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA