Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 2232931..2233457 | Replicon | chromosome |
| Accession | NZ_CP099590 | ||
| Organism | Escherichia coli strain WG1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | NHF37_RS10790 | Protein ID | WP_000323025.1 |
| Coordinates | 2233170..2233457 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | S1F6D3 |
| Locus tag | NHF37_RS10785 | Protein ID | WP_000534858.1 |
| Coordinates | 2232931..2233170 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NHF37_RS10730 (2227958) | 2227958..2228725 | - | 768 | Protein_2108 | exonuclease | - |
| NHF37_RS10735 (2228818) | 2228818..2229009 | - | 192 | WP_001083297.1 | lysis protein YdfD | - |
| NHF37_RS10740 (2229006) | 2229006..2229194 | - | 189 | WP_000854559.1 | cell division inhibition protein DicB | - |
| NHF37_RS10745 (2229762) | 2229762..2229980 | - | 219 | WP_001171942.1 | protein YdfC | - |
| NHF37_RS23190 (2230010) | 2230010..2230138 | - | 129 | WP_000344964.1 | protein YdfB | - |
| NHF37_RS10750 (2230140) | 2230140..2230295 | - | 156 | WP_000379575.1 | DUF1391 family protein | - |
| NHF37_RS10755 (2230462) | 2230462..2230869 | - | 408 | WP_000448564.1 | DNA-binding transcriptional dual regulator DicA | - |
| NHF37_RS10760 (2230953) | 2230953..2231183 | + | 231 | WP_000920568.1 | dicB transcriptional regulator DicC | - |
| NHF37_RS10765 (2231167) | 2231167..2231445 | + | 279 | Protein_2116 | protein YdfX | - |
| NHF37_RS10770 (2231480) | 2231480..2231629 | + | 150 | WP_011443592.1 | protein YdfW | - |
| NHF37_RS10775 (2232066) | 2232066..2232398 | - | 333 | WP_001301033.1 | FlxA-like family protein | - |
| NHF37_RS10780 (2232601) | 2232601..2232906 | - | 306 | WP_001326990.1 | protein YdfV | - |
| NHF37_RS10785 (2232931) | 2232931..2233170 | + | 240 | WP_000534858.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| NHF37_RS10790 (2233170) | 2233170..2233457 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| NHF37_RS10795 (2233529) | 2233529..2233684 | + | 156 | WP_000813254.1 | type I toxin-antitoxin system toxin HokD | - |
| NHF37_RS10800 (2233901) | 2233901..2234152 | + | 252 | WP_000980994.1 | protein Rem | - |
| NHF37_RS10805 (2234219) | 2234219..2234497 | + | 279 | WP_012304870.1 | hypothetical protein | - |
| NHF37_RS10810 (2234499) | 2234499..2235548 | + | 1050 | WP_001265198.1 | DUF968 domain-containing protein | - |
| NHF37_RS10815 (2235562) | 2235562..2236314 | + | 753 | WP_001047135.1 | antitermination protein | - |
| NHF37_RS10820 (2236592) | 2236592..2236681 | - | 90 | WP_120795389.1 | hypothetical protein | - |
| NHF37_RS10825 (2236736) | 2236736..2236948 | - | 213 | WP_000087756.1 | cold shock-like protein CspF | - |
| NHF37_RS10830 (2237249) | 2237249..2237464 | + | 216 | WP_000066484.1 | cold shock-like protein CspB | - |
| NHF37_RS10835 (2237828) | 2237828..2237998 | - | 171 | WP_211180497.1 | putative zinc-binding protein YnfU | - |
| NHF37_RS10840 (2238218) | 2238218..2238433 | + | 216 | WP_000839590.1 | phage lysis protein EssD | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2213004..2249588 | 36584 | ||
| inside | Prophage | - | - | 2219597..2250451 | 30854 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|