Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 1722106..1722632 | Replicon | chromosome |
| Accession | NZ_CP114891 | ||
| Organism | Escherichia coli strain CM2 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | O6Q44_RS08425 | Protein ID | WP_000323025.1 |
| Coordinates | 1722345..1722632 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | S1F6D3 |
| Locus tag | O6Q44_RS08420 | Protein ID | WP_000534858.1 |
| Coordinates | 1722106..1722345 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O6Q44_RS08360 (1717133) | 1717133..1717900 | - | 768 | Protein_1630 | exonuclease | - |
| O6Q44_RS08365 (1717993) | 1717993..1718184 | - | 192 | WP_001083297.1 | lysis protein YdfD | - |
| O6Q44_RS08370 (1718181) | 1718181..1718369 | - | 189 | WP_000854559.1 | cell division inhibition protein DicB | - |
| O6Q44_RS08375 (1718937) | 1718937..1719155 | - | 219 | WP_001171942.1 | protein YdfC | - |
| O6Q44_RS08380 (1719185) | 1719185..1719313 | - | 129 | WP_000344964.1 | protein YdfB | - |
| O6Q44_RS08385 (1719315) | 1719315..1719470 | - | 156 | WP_000379575.1 | DUF1391 family protein | - |
| O6Q44_RS08390 (1719637) | 1719637..1720044 | - | 408 | WP_000448564.1 | DNA-binding transcriptional dual regulator DicA | - |
| O6Q44_RS08395 (1720128) | 1720128..1720358 | + | 231 | WP_000920568.1 | dicB transcriptional regulator DicC | - |
| O6Q44_RS08400 (1720342) | 1720342..1720620 | + | 279 | Protein_1638 | protein YdfX | - |
| O6Q44_RS08405 (1720655) | 1720655..1720804 | + | 150 | WP_011443592.1 | protein YdfW | - |
| O6Q44_RS08410 (1721241) | 1721241..1721573 | - | 333 | WP_001301033.1 | FlxA-like family protein | - |
| O6Q44_RS08415 (1721776) | 1721776..1722081 | - | 306 | WP_001326990.1 | protein YdfV | - |
| O6Q44_RS08420 (1722106) | 1722106..1722345 | + | 240 | WP_000534858.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| O6Q44_RS08425 (1722345) | 1722345..1722632 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| O6Q44_RS08430 (1722704) | 1722704..1722859 | + | 156 | WP_000813254.1 | type I toxin-antitoxin system toxin HokD | - |
| O6Q44_RS08435 (1723076) | 1723076..1723327 | + | 252 | WP_000980994.1 | protein Rem | - |
| O6Q44_RS08440 (1723394) | 1723394..1723672 | + | 279 | WP_012304870.1 | hypothetical protein | - |
| O6Q44_RS08445 (1723674) | 1723674..1724723 | + | 1050 | WP_001265198.1 | DUF968 domain-containing protein | - |
| O6Q44_RS08450 (1724737) | 1724737..1725489 | + | 753 | WP_001047135.1 | antitermination protein | - |
| O6Q44_RS08455 (1725767) | 1725767..1725856 | - | 90 | WP_120795389.1 | hypothetical protein | - |
| O6Q44_RS08460 (1725911) | 1725911..1726123 | - | 213 | WP_000087756.1 | cold shock-like protein CspF | - |
| O6Q44_RS08465 (1726424) | 1726424..1726639 | + | 216 | WP_000066484.1 | cold shock-like protein CspB | - |
| O6Q44_RS08470 (1727003) | 1727003..1727173 | - | 171 | WP_211180497.1 | putative zinc-binding protein YnfU | - |
| O6Q44_RS08475 (1727393) | 1727393..1727608 | + | 216 | WP_000839590.1 | phage lysis protein EssD | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 1702179..1739626 | 37447 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|