Detailed information of TA system TA006279

Experimentally validated

Overview

TA module

• Type: II
• Classification (family/domain): yjhX-yjhQ/-
• Location: 4533239..4534053
• Replicon: chromosome
• Accession: NC_000913
• Organism: Escherichia coli str. K-12 substr. MG1655

Toxin (Protein)

• Gene name: yjhX
• Uniprot ID: Q2EEU2
• Locus tag: b4566
• Protein ID: YP_588477.1
• Coordinates: 4533796..4534053 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: yjhQ
• Uniprot ID: P39368
• Locus tag: b4307
• Protein ID: NP_418727.1
• Coordinates: 4533239..4533784 (-)
• Length: 182 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
b4304	4528930..4530243	-	1314	NP_418724.1	putative PTS enzyme IIC component SgcC	-
b4565	4530255..4530533	-	279	YP_588476.1	putative PTS enzyme IIB component SgcB	-
b4305	4530530..4531651	-	1122	NP_418725.4	putative endoglucanase with Zn-dependent exopeptidase domain	-
b4306	4532437..4533183	-	747	NP_418726.1	putative methyltransferase YjhP	-
b4307	4533239..4533784	-	546	NP_418727.1	putative acetyltransferase TopAI antitoxin YjhQ	Antitoxin
b4566	4533796..4534053	-	258	YP_588477.1	toxin of the TopAI-YjhQ toxin-antitoxin system, TopA inhibitor	Toxin
b4802	4536597..4536695	+	99	YP_010051216.1	protein YthB	-
b4309	4536614..4537594	-	981	NP_418729.1	N-acetyl-9-O-acetylneuraminate esterase	-
b4310	4537659..4538765	-	1107	NP_418730.4	N-acetylneuraminate mutarotase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View HG738867 Escherichia coli str. K-12 substr. MC4100 Genomic island TA020089 4419085..4430625 0.004 View NC_012759 Escherichia coli BW2952 Genomic island TA023876 4469997..4481537 0.004 View NC_017638 Escherichia coli DH1 Genomic island TA027426 4513009..4524807 0 View NZ_CP009273 Escherichia coli BW25113 Genomic island TA048705 4523056..4534846 0 View HG738867 Escherichia coli str. K-12 substr. MC4100 Genomic island TA020089 4419085..4430625 0.004 View NC_007779 Escherichia coli str. K-12 substr. W3110 Genomic island TA021460 4537919..4549709 0 View NZ_CP017979 Escherichia coli str. K-12 substr. W3110 strain K-12 substr. ZK126 Genomic island TA068445 4432698..4444488 0 View NZ_HG738867 Escherichia coli str. K-12 substr. MC4100 strain K-12 Genomic island TA285034 4419085..4430625 0.004 View NZ_AP022069 Escherichia coli strain WP4-W18-ESBL-09 Genomic island TA034376 4451543..4459863 0.01 View NZ_AP022207 Escherichia coli strain WP7-S18-ESBL-09 Genomic island TA034931 4496613..4507640 0.002 View NZ_AP022650 Escherichia coli strain 09-02E Genomic island TA036473 4973972..4985762 0.001 View NZ_CP008801 Escherichia coli KLY Genomic island TA047531 4610098..4621888 0 View NZ_CP010140 Escherichia coli strain D3 Genomic island TA050699 365263..377053 0.001 View NZ_CP010440 Escherichia coli K-12 strain K-12 MG1655 Genomic island TA052489 652082..663872 0 View NZ_CP010443 Escherichia coli K-12 strain K-12 MG1655 Genomic island TA052612 650086..661876 0 View NZ_CP011320 Escherichia coli strain SQ37 Genomic island TA053866 4525048..4536838 0 View NZ_CP011321 Escherichia coli strain SQ88 Genomic island TA053909 4502468..4514258 0 View NZ_CP011322 Escherichia coli strain SQ110 Genomic island TA053952 4496722..4508512 0 View NZ_CP011324 Escherichia coli strain SQ2203 Genomic island TA053995 4496888..4508678 0 View NZ_CP011342 Escherichia coli K-12 substr. GM4792 Genomic island TA054080 4513929..4525719 0 View NZ_CP011343 Escherichia coli K-12 substr. GM4792 Genomic island TA054119 4513243..4525033 0 View NZ_CP011495 Escherichia coli strain NCM3722 isolate K-12 Genomic island TA054304 1110109..1121898 0 View NZ_CP012125 Escherichia coli strain DH1Ec095 Genomic island TA055862 4505801..4517600 0 View NZ_CP012126 Escherichia coli strain DH1Ec104 Genomic island TA055905 4503941..4515740 0 View NZ_CP012127 Escherichia coli strain DH1Ec169 Genomic island TA055948 4501100..4512899 0 View NZ_CP014225 Escherichia coli str. K-12 substr. MG1655 strain K-12 Genomic island TA060393 2730328..2742118 0 View NZ_CP014270 Escherichia coli K-12 strain K-12 DHB4 Genomic island TA060549 4438440..4450230 0 View NZ_CP014272 Escherichia coli K-12 strain K-12 C3026 Genomic island TA060601 4636842..4648632 0 View NZ_CP019629 Escherichia coli strain MGY Genomic island TA073098 4534837..4546627 0 View NZ_CP022229 Escherichia coli strain WCHEC96200 Genomic island TA078705 2761077..2772866 0.001 View NZ_CP023960 Escherichia coli strain FDAARGOS_448 Genomic island TA086478 2768858..2779885 0.002 View NZ_CP025268 Escherichia coli str. K-12 substr. MG1655 strain K-12 Genomic island TA090018 4535154..4546943 0 View NZ_CP025401 Escherichia coli strain MS8345 Genomic island TA090302 5077482..5089273 0.001 View NZ_CP026026 Escherichia coli strain CAR Genomic island TA092782 4436233..4448023 0 View NZ_CP026027 Escherichia coli strain LIM Genomic island TA092825 4516555..4528345 0 View NZ_CP026028 Escherichia coli strain CIT Genomic island TA092868 4531260..4543050 0 View NZ_CP026342 Escherichia coli strain 9FA Genomic island TA093883 4533239..4545029 0 View NZ_CP026343 Escherichia coli strain 9A Genomic island TA093926 4533234..4545024 0 View NZ_CP026344 Escherichia coli strain 8FA Genomic island TA093969 4533241..4545031 0 View NZ_CP026347 Escherichia coli strain 7A Genomic island TA094098 4533234..4545024 0 View NZ_CP026348 Escherichia coli strain 6FA Genomic island TA094141 4533240..4545030 0 View NZ_CP026349 Escherichia coli strain 6A Genomic island TA094184 4533185..4544975 0 View NZ_CP026350 Escherichia coli strain 5FA Genomic island TA094227 4533241..4545031 0 View NZ_CP026351 Escherichia coli strain 5A Genomic island TA094270 4533240..4545030 0 View NZ_CP026352 Escherichia coli strain 4FA Genomic island TA094313 4533241..4545031 0 View NZ_CP026353 Escherichia coli strain 4A Genomic island TA094356 4533241..4545031 0 View NZ_CP026355 Escherichia coli strain 3A Genomic island TA094442 4533241..4545031 0 View NZ_CP026356 Escherichia coli strain 2FA Genomic island TA094485 4533240..4545030 0 View NZ_CP026357 Escherichia coli strain 2F_0 Genomic island TA094528 4533240..4545030 0 View NZ_CP026359 Escherichia coli strain 2_0 Genomic island TA094614 4533240..4545030 0 View NZ_CP026360 Escherichia coli strain 1FA Genomic island TA094657 4533241..4545031 0 View NZ_CP026361 Escherichia coli strain 1A Genomic island TA094700 4533249..4545039 0 View NZ_CP026491 Escherichia coli strain HS13-1 Genomic island TA094988 3590775..3602566 0.001 View NZ_CP026612 Escherichia coli strain DTU-1 Genomic island TA095265 1584820..1596610 0 View NZ_CP026853 Escherichia coli strain MS7163 Genomic island TA096507 4918012..4929804 0.01 View NZ_CP028702 Escherichia coli strain J53 Genomic island TA102938 287975..299765 0 View NZ_CP028703 Escherichia coli strain ME8067 Genomic island TA102982 781226..794215 0.003 View NZ_CP028760 Escherichia coli strain A14 Genomic island TA103780 669746..681536 0.006 View NZ_CP029238 Escherichia coli strain CJ236 Genomic island TA105272 4533239..4545029 0 View NZ_CP030240 Escherichia coli strain ER1709 Genomic island TA107370 2096258..2108029 0 View NZ_CP032679 Escherichia coli str. K-12 substr. MG1655 strain K-12 Genomic island TA112129 4523130..4534920 0 View NZ_CP034658 Escherichia coli strain ATCC 98082 Genomic island TA116336 4505130..4516920 0 View NZ_CP040456 Escherichia coli strain UPEC132 Genomic island TA125864 4365455..4376484 0.002 View NZ_CP040643 Escherichia coli strain BE104 Genomic island TA126287 4666710..4678500 0 View NZ_CP040663 Escherichia coli strain EK2009 Genomic island TA126374 4496617..4508406 0 View NZ_CP040664 Escherichia coli strain KR2009 Genomic island TA126417 4493113..4504902 0 View NZ_CP042843 Escherichia coli strain JME67 Genomic island TA136070 602194..613984 0 View NZ_CP042844 Escherichia coli strain JME66 Genomic island TA136113 597313..609103 0 View NZ_CP042845 Escherichia coli strain JME65 Genomic island TA136156 602194..613984 0 View NZ_CP042846 Escherichia coli strain JME64 Genomic island TA136199 597313..609103 0 View NZ_CP043295 Escherichia coli strain WCHEC040047 Genomic island TA138271 1909583..1920610 0.002 View NZ_CP043950 Escherichia coli strain ST95-32 Genomic island TA139617 683687..695478 0.001 View NZ_CP044410 Escherichia coli strain ecMN1F Genomic island TA140872 598956..610746 0 View NZ_CP049196 Escherichia coli strain E118 Genomic island TA150918 3895947..3906974 0.002 View NZ_CP049197 Escherichia coli strain E597 Genomic island TA150946 3587909..3598936 0.002 View NZ_CP049198 Escherichia coli strain E686 Genomic island TA150973 3290150..3301176 0.003 View NZ_CP049839 Escherichia coli strain UPEC-455U/190220 Genomic island TA151641 574399..586189 0.001 View NZ_CP049852 Escherichia coli strain UPEC-774U/190308 Genomic island TA151708 575343..587133 0.001 View NZ_CP050998 Escherichia coli O39:NM str. F8704-2 Genomic island TA153481 2308242..2320033 0.009 View NZ_CP051719 Escherichia coli strain SCU-116 Genomic island TA155026 3571249..3583040 0.001 View NZ_CP053251 Escherichia coli strain SCU-204 Genomic island TA156417 1297780..1309569 0.001 View NZ_CP053605 Escherichia coli strain NEB_Turbo Genomic island TA157151 4421973..4434961 0.003 View NZ_CP053662 Escherichia coli strain eco-241 Genomic island TA157377 4500016..4512243 0.004 View NZ_CP054161 Escherichia coli strain STO_Bone2 Genomic island TA158811 234138..245165 0.002 View NZ_CP054214 Escherichia coli strain EcPF40 Genomic island TA158956 574039..585829 0.001 View NZ_CP054665 Escherichia coli strain IGC_EcoliInv_1.1 Genomic island TA160068 4585030..4596820 0 View NZ_CP056036 Escherichia coli strain EC31 Genomic island TA162541 4523017..4535244 0.004 View NZ_CP058948 Escherichia coli strain SY3626C5 Genomic island TA167983 287975..299765 0 View NZ_CP059043 Escherichia coli strain SY3626C1 Genomic island TA168111 287975..299765 0 View NZ_CP060953 Escherichia coli strain EC8 Genomic island TA171732 3513272..3525062 0.001 View NZ_CP062239 Escherichia coli strain AML001_ev03 Genomic island TA173668 4523056..4534846 0 View NZ_CP062240 Escherichia coli strain AML001_ev02 Genomic island TA173711 4524255..4536045 0 View NZ_CP062241 Escherichia coli strain AML001_ev01 Genomic island TA173754 4524255..4536045 0 View NZ_CP062242 Escherichia coli strain AML001_par Genomic island TA173797 4523056..4534846 0 View NZ_CP062244 Escherichia coli strain AML003_ev02 Genomic island TA173883 4523056..4534846 0 View NZ_CP062245 Escherichia coli strain AML003_ev01 Genomic island TA173926 4523055..4534845 0 View NZ_CP062246 Escherichia coli strain AML003_par Genomic island TA173969 4523056..4534846 0 View NZ_CP062247 Escherichia coli strain AML002_ev03 Genomic island TA174012 4524259..4536049 0 View NZ_CP062248 Escherichia coli strain AML002_ev02 Genomic island TA174055 4523057..4534847 0 View NZ_CP062249 Escherichia coli strain AML002_ev01 Genomic island TA174098 4524255..4536045 0 View NZ_CP062250 Escherichia coli strain AML002_par Genomic island TA174141 4523056..4534846 0 View NZ_CP064103 Escherichia coli strain IR53017 Genomic island TA180144 4502327..4513354 0.002 View NZ_CP064678 Escherichia coli K-12 strain CETR3G40 Genomic island TA181449 4523057..4534847 0 View NZ_CP064679 Escherichia coli K-12 strain CETR2G40 Genomic island TA181492 4523057..4534847 0 View NZ_CP064680 Escherichia coli K-12 strain CETR1G40 Genomic island TA181535 4523054..4534844 0 View NZ_CP064681 Escherichia coli K-12 strain BZKR3G40 Genomic island TA181578 4523062..4534853 0 View NZ_CP064682 Escherichia coli K-12 strain BZKR2G40 Genomic island TA181621 4523056..4534847 0 View NZ_CP066836 Escherichia coli strain Ec-FL1-1X Genomic island TA185155 2478774..2489802 0.002 View NZ_CP067299 Escherichia coli strain ABW_A33 Genomic island TA186000 505435..518424 0.003 View NZ_CP067303 Escherichia coli strain ABW_A32 Genomic island TA186032 505435..518424 0.003 View NZ_CP068279 Escherichia coli strain CY708 Genomic island TA186996 1045931..1057720 0 View NZ_CP068281 Escherichia coli strain CY706 Genomic island TA187037 1100073..1111862 0 View NZ_CP069132 Escherichia coli BW25113 substr. CHXR1G20 Genomic island TA189941 4523052..4534842 0 View NZ_CP069133 Escherichia coli BW25113 substr. CHXR2G20 Genomic island TA189984 4523056..4534846 0 View NZ_CP069528 Escherichia coli strain FDAARGOS_1252 Genomic island TA190816 3464756..3475784 0.002 View NZ_CP069935 Escherichia coli strain FDAARGOS_1302 Genomic island TA192161 4522868..4534659 0.001 View NZ_CP070007 Escherichia coli strain FDAARGOS_1288 Genomic island TA192623 1102912..1115139 0.004 View NZ_CP072054 Escherichia coli strain K1508 Genomic island TA197281 4418584..4430124 0.004 View NZ_CP076344 Escherichia coli strain AVS0096 Genomic island TA205514 574038..585828 0.001 View NZ_CP077969 Escherichia coli strain JM83 Genomic island TA208777 4448254..4460044 0 View NZ_CP079991 Escherichia coli strain KMS2005 Genomic island TA210452 783600..795390 0 View NZ_CP079993 Escherichia coli strain EV36 Genomic island TA210516 783600..795390 0 View NZ_CP080155 Escherichia coli strain PK8261 Genomic island TA211118 4322320..4333348 0.002 View NZ_CP080163 Escherichia coli strain PK8275 Genomic island TA211162 4930904..4941932 0.002 View NZ_CP083410 Escherichia coli strain RP437 Genomic island TA216393 4533103..4544893 0 View NZ_CP085063 Escherichia coli strain P31_YH1_02.21 Genomic island TA220306 2507111..2515431 0.01 View NZ_CP086334 Escherichia coli strain EBJ003 Genomic island TA222995 2657763..2668790 0.002 View NZ_CP087136 Escherichia coli strain JW5503 Genomic island TA224853 4522226..4534016 0 View NZ_CP087287 Escherichia coli strain APEC 16-1068 Genomic island TA225215 584569..596362 0.001 View NZ_CP087564 Escherichia coli strain CM2010-0578/1 Genomic island TA225494 3894246..3906038 0.006 View NZ_CP090196 Escherichia coli strain YL3 Genomic island TA230206 4405082..4416109 0.002 View NZ_CP091065 Escherichia coli strain DOC14 Genomic island TA232637 4522226..4534016 0 View NZ_CP091682 Escherichia coli strain KKo003 Genomic island TA234490 573406..585196 0.001 View NZ_CP092702 Escherichia coli strain S-P-C-029.01 Genomic island TA237002 4533186..4544976 0 View NZ_CP093368 Escherichia coli strain EV36 mutant 1a Genomic island TA238240 783600..795390 0 View NZ_CP095518 Escherichia coli strain GN02350 Genomic island TA242177 1336759..1347788 0.002 View NZ_CP102378 Escherichia coli strain JB41 Genomic island TA253523 4543875..4555665 0 View NZ_CP102379 Escherichia coli strain BM28 lysU Genomic island TA253557 4409021..4422150 0.003 View NZ_CP102380 Escherichia coli strain BM28 Genomic island TA253591 4410629..4423758 0.003 View NZ_CP102488 Escherichia coli O15:H18 strain ST69 Genomic island TA253748 2904224..2915252 0.002 View NZ_CP103633 Escherichia coli strain 2900 Genomic island TA255942 4407363..4418390 0.002 View NZ_CP103718 Escherichia coli strain 1579 Genomic island TA256341 4348161..4359188 0.002 View NZ_CP103718 Escherichia coli strain 1579 Genomic island TA256341 4350868..4359188 0.01 View NZ_CP110996 Escherichia coli strain XYEH3783 Genomic island TA264699 3468430..3480220 0.001 View NZ_CP116103 Escherichia coli strain DETEC-P836 Genomic island TA267959 574507..586297 0.001 View NZ_CP116115 Escherichia coli strain DETEC-P793 Genomic island TA268054 575407..587197 0.001 View NZ_CP116191 Escherichia coli strain DETEC-E1070 Genomic island TA268361 574487..586277 0.001 View NZ_CP116194 Escherichia coli strain DETEC-E1005 Genomic island TA268388 574497..586287 0.001 View NZ_CP122316 Escherichia coli strain HT-946 Genomic island TA276675 2863259..2875049 0 View NZ_CP122318 Escherichia coli strain HT873X1 Genomic island TA276737 2895058..2906848 0 View NZ_CP122319 Escherichia coli strain BW25113 Genomic island TA276757 2332634..2344424 0 View NZ_CP126928 Escherichia coli O2:K1:H4 strain APEC E12053 Genomic island TA283066 4139608..4150637 0.002 View NZ_LM993812 Escherichia coli strain K-12 substr. HMS174 Genomic island TA285415 4476447..4488237 0 View NZ_LN832404 Escherichia coli K-12 substr. AG100 Genomic island TA285673 4529713..4541503 0 View NZ_LR134227 Escherichia coli strain NCTC9102 Genomic island TA287182 3918538..3929566 0.002 View NZ_LR740758 Escherichia coli strain BEN5202 isolate laying hen 51 weeks old Genomic island TA288974 5013926..5025717 0.001 View NZ_LR881938 Escherichia coli str. K-12 substr. MG1655 strain K-12 Genomic island TA289531 4516733..4528523 0 View NZ_LR890410 Escherichia coli isolate MSB2_1A-sc-2280429 Genomic island TA290924 3443589..3455379 0.001 View NZ_LT615377 Escherichia coli isolate 106 Genomic island TA293359 4529713..4541503 0 View NZ_LT615378 Escherichia coli isolate 103 Genomic island TA293390 4529713..4541503 0 View NC_007779 Escherichia coli str. K-12 substr. W3110 Genomic island TA021460 4537919..4549709 0 View NC_012759 Escherichia coli BW2952 Genomic island TA023876 4469997..4481537 0.004 View NC_017638 Escherichia coli DH1 Genomic island TA027426 4513009..4524807 0 View NZ_CP009273 Escherichia coli BW25113 Genomic island TA048705 4523056..4534846 0 View NZ_CP017979 Escherichia coli str. K-12 substr. W3110 strain K-12 substr. ZK126 Genomic island TA068445 4432698..4444488 0 View NZ_HG738867 Escherichia coli str. K-12 substr. MC4100 strain K-12 Genomic island TA285034 4419085..4430625 0.004	inside	Genomic island	-	fimB / fimE / fimA / fimI / fimC	4533239..4545029	11790

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Putative toxin of bacterial toxin-antitoxin pair (1-85)

Antitoxin

• GNAT domain (18-121)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 9734.29 Da
• Isoelectric Point: 11.0090

>T6279 YP_588477.1 NC_000913:c4534053-4533796 [Escherichia coli str. K-12 substr. MG1655]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR

Nucleotide

• Length: 258 bp

>T6279 NC_000913:c4534053-4533796 [Escherichia coli str. K-12 substr. MG1655]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin

Protein

• Length: 182 a.a.
• Molecular weight: 19956.90 Da
• Isoelectric Point: 6.3277

>AT6279 NP_418727.1 NC_000913:c4533784-4533239 [Escherichia coli str. K-12 substr. MG1655]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT

Nucleotide

• Length: 546 bp

>AT6279 NC_000913:c4533784-4533239 [Escherichia coli str. K-12 substr. MG1655]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Structures

Toxin

• AlphaFold DB: Q2EEU2

Antitoxin

• AlphaFold DB: P39368

References

(1) Yoshihiro Yamaguchi et al. (2015) An endogenous protein inhibitor, YjhX (TopAI), for topoisomerase I from Escherichia coli. Nucleic Acids Research 43(21):10387-96. [PubMed:26553797]


 experimental literature