Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX(toxin) |
Location | 4522868..4523682 | Replicon | chromosome |
Accession | NZ_CP069935 | ||
Organism | Escherichia coli strain FDAARGOS_1302 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | I6K32_RS21930 | Protein ID | WP_001054376.1 |
Coordinates | 4523425..4523682 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | A0A8E0IVE5 |
Locus tag | I6K32_RS21925 | Protein ID | WP_001350781.1 |
Coordinates | 4522868..4523413 (-) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6K32_RS21895 (4518559) | 4518559..4519872 | - | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
I6K32_RS21900 (4519884) | 4519884..4520162 | - | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
I6K32_RS21905 (4520159) | 4520159..4521280 | - | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
I6K32_RS21910 (4521525) | 4521525..4521641 | - | 117 | Protein_4318 | VOC family protein | - |
I6K32_RS21915 (4521679) | 4521679..4521897 | - | 219 | Protein_4319 | hypothetical protein | - |
I6K32_RS21920 (4522066) | 4522066..4522812 | - | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
I6K32_RS21925 (4522868) | 4522868..4523413 | - | 546 | WP_001350781.1 | N-acetyltransferase | Antitoxin |
I6K32_RS21930 (4523425) | 4523425..4523682 | - | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
I6K32_RS25225 (4524173) | 4524173..4524304 | - | 132 | WP_001309182.1 | hypothetical protein | - |
I6K32_RS21940 (4524420) | 4524420..4525660 | + | 1241 | Protein_4324 | helicase YjhR | - |
I6K32_RS25230 (4525928) | 4525928..4526133 | - | 206 | Protein_4325 | HNH endonuclease | - |
I6K32_RS21945 (4526243) | 4526243..4527223 | - | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
I6K32_RS21950 (4527288) | 4527288..4528394 | - | 1107 | WP_001309184.1 | N-acetylneuraminate epimerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | fimB / fimE / fimA / fimI / fimC | 4522868..4534659 | 11791 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T192161 WP_001054376.1 NZ_CP069935:c4523682-4523425 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
>T192161 NZ_CP092107:c1694632-1694129 [Vibrio sp. JC009]
ATGATGAATTCGGTACTTCTGGACAAATCGAAACACAACAGAAATAGATTCAATTGTGGCATTGAAGCCCTCAATAACTA
TCTAAAAGTAATGGCTAATCAGCAAGCCAAGAAAGACAACACCAGAACTTTTGTTCTGGAAGACGAAAATGATAATTCGT
ATATCATCGGCTTTTATACATTGACGATGACACCAATTAACTTGGAGGCTTTGCCCGATAAGTTACAGAAAAAGCACCAA
TCATCAACTTCCGGAGGTCTCATTGCTCGCTTGGCTATTGATGAGCGCTACAAAGGAAAAGGATTTGGCGAATGGTTGCT
TATTGATGCTCTACGAAAATTATTGACCGCTAGTGACAGCGTGGCATTCCCTGTTGTAATTGTTGATGCCAAAGATGGAG
CAAAACAGTTCTACGAGCGCTATGGATTTCAGGCATTTCAAAGTGCAGAAAACAAATTGTTCATCACGATTTCTGATGTC
AGAGAGAGCTTGGAGTATCAGTAA
ATGATGAATTCGGTACTTCTGGACAAATCGAAACACAACAGAAATAGATTCAATTGTGGCATTGAAGCCCTCAATAACTA
TCTAAAAGTAATGGCTAATCAGCAAGCCAAGAAAGACAACACCAGAACTTTTGTTCTGGAAGACGAAAATGATAATTCGT
ATATCATCGGCTTTTATACATTGACGATGACACCAATTAACTTGGAGGCTTTGCCCGATAAGTTACAGAAAAAGCACCAA
TCATCAACTTCCGGAGGTCTCATTGCTCGCTTGGCTATTGATGAGCGCTACAAAGGAAAAGGATTTGGCGAATGGTTGCT
TATTGATGCTCTACGAAAATTATTGACCGCTAGTGACAGCGTGGCATTCCCTGTTGTAATTGTTGATGCCAAAGATGGAG
CAAAACAGTTCTACGAGCGCTATGGATTTCAGGCATTTCAAAGTGCAGAAAACAAATTGTTCATCACGATTTCTGATGTC
AGAGAGAGCTTGGAGTATCAGTAA
Antitoxin
Download Length: 182 a.a. Molecular weight: 19974.91 Da Isoelectric Point: 6.3277
>AT192161 WP_001350781.1 NZ_CP069935:c4523413-4522868 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAFIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAFIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
>AT192161 NZ_CP092107:c1694901-1694629 [Vibrio sp. JC009]
ATGGCAGCTACATTGCCTCGCATCACCGCCAGGGTTGATGTCGATACACAAGATTTACTTACTAAAGCTGCTGCGATTGC
AGGTATGTCTAGTATTAATTCATTTGTTCTAAGTGCTGCAATTGAGAAAGCAAAAGAGGTTATCGAACGTGAACAAGCTC
TAAGGCTTAGTCAAAAGGATGCATTGTTGCTTATGGAAGCGCTTGACCGACCTGCAAAACCAAACGCAAAATTGAAAGCT
GCAGCTAAACGTTATGAGCACAAAACTCAATGA
ATGGCAGCTACATTGCCTCGCATCACCGCCAGGGTTGATGTCGATACACAAGATTTACTTACTAAAGCTGCTGCGATTGC
AGGTATGTCTAGTATTAATTCATTTGTTCTAAGTGCTGCAATTGAGAAAGCAAAAGAGGTTATCGAACGTGAACAAGCTC
TAAGGCTTAGTCAAAAGGATGCATTGTTGCTTATGGAAGCGCTTGACCGACCTGCAAAACCAAACGCAAAATTGAAAGCT
GCAGCTAAACGTTATGAGCACAAAACTCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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