Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 574487..575301 | Replicon | chromosome |
Accession | NZ_CP116191 | ||
Organism | Escherichia coli strain DETEC-E1070 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | PIC72_RS02770 | Protein ID | WP_001054376.1 |
Coordinates | 575044..575301 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | S1NWL7 |
Locus tag | PIC72_RS02765 | Protein ID | WP_001540600.1 |
Coordinates | 574487..575032 (-) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PIC72_RS02735 (570178) | 570178..571491 | - | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
PIC72_RS02740 (571503) | 571503..571781 | - | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
PIC72_RS02745 (571778) | 571778..572899 | - | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
PIC72_RS02750 (573144) | 573144..573260 | - | 117 | Protein_532 | VOC family protein | - |
PIC72_RS02755 (573298) | 573298..573516 | - | 219 | Protein_533 | hypothetical protein | - |
PIC72_RS02760 (573685) | 573685..574431 | - | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
PIC72_RS02765 (574487) | 574487..575032 | - | 546 | WP_001540600.1 | N-acetyltransferase | Antitoxin |
PIC72_RS02770 (575044) | 575044..575301 | - | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
PIC72_RS02775 (575792) | 575792..575923 | - | 132 | WP_001309182.1 | hypothetical protein | - |
PIC72_RS02780 (576039) | 576039..577279 | + | 1241 | Protein_538 | helicase YjhR | - |
PIC72_RS02785 (577547) | 577547..577752 | - | 206 | Protein_539 | HNH endonuclease | - |
PIC72_RS02790 (577862) | 577862..578842 | - | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
PIC72_RS02795 (578907) | 578907..580013 | - | 1107 | WP_001774143.1 | N-acetylneuraminate epimerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | fimB / fimE / fimA / fimI / fimC | 574487..586277 | 11790 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T268361 WP_001054376.1 NZ_CP116191:c575301-575044 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 182 a.a. Molecular weight: 19926.87 Da Isoelectric Point: 6.3277
>AT268361 WP_001540600.1 NZ_CP116191:c575032-574487 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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