288974

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 5013926..5014740 Replicon chromosome
Accession NZ_LR740758
Organism Escherichia coli strain BEN5202 isolate laying hen 51 weeks old

Toxin (Protein)


Gene name yjhX Uniprot ID S1PA82
Locus tag APEC5202_RS24380 Protein ID WP_001054376.1
Coordinates 5014483..5014740 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A8E0IVE5
Locus tag APEC5202_RS24375 Protein ID WP_001350781.1
Coordinates 5013926..5014471 (-) Length 182 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APEC5202_RS24350 5009617..5010930 - 1314 WP_000460843.1 galactitol-specific PTS transporter subunit IIC -
APEC5202_RS24355 5010942..5011220 - 279 WP_000722973.1 PTS sugar transporter subunit IIB -
APEC5202_RS24360 5011217..5012338 - 1122 WP_000010829.1 M42 family metallopeptidase -
APEC5202_RS26880 5012583..5012699 - 117 Protein_4771 VOC family protein -
APEC5202_RS24365 5012737..5012955 - 219 Protein_4772 hypothetical protein -
APEC5202_RS24370 5013124..5013870 - 747 WP_000354251.1 class I SAM-dependent methyltransferase -
APEC5202_RS24375 5013926..5014471 - 546 WP_001350781.1 N-acetyltransferase Antitoxin
APEC5202_RS24380 5014483..5014740 - 258 WP_001054376.1 hypothetical protein Toxin
APEC5202_RS24385 5015117..5015362 - 246 Protein_4776 GNAT family N-acetyltransferase -
APEC5202_RS24395 5015478..5016718 + 1241 Protein_4777 DNA helicase -
APEC5202_RS24400 5017301..5018281 - 981 WP_000991438.1 9-O-acetyl-N-acetylneuraminic acid deacetylase -
APEC5202_RS24405 5018346..5019452 - 1107 WP_001309184.1 N-acetylneuraminate epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - fimB / fimE / fimA / fimI / fimC 5013926..5025717 11791


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(18-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9734.29 Da        Isoelectric Point: 11.0090

>T288974 WP_001054376.1 NZ_LR740758:c5014740-5014483 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 182 a.a.        Molecular weight: 19974.91 Da        Isoelectric Point: 6.3277

>AT288974 WP_001350781.1 NZ_LR740758:c5014471-5013926 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAFIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT

Download         Length: 546 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1PA82

Antitoxin

Source ID Structure

References