Detailed information of TA system TA000439

Experimentally validated

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/AbrB-PIN
• Location: 3195156..3195781
• Replicon: chromosome
• Accession: NC_003197
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: STM3033
• Protein ID: NP_461950.1
• Coordinates: 3195162..3195560 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: STM3034
• Protein ID: NP_461951.1
• Coordinates: 3195560..3195787 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
STM3029	3191126..3191836	-	711	NP_461946.3	putative fimbrial-like protein	-
STM3030	3192429..3193061	-	633	NP_461947.1	putative periplasmic protein	-
STM3031	3193108..3193644	-	537	NP_461948.1	ail and ompX-like protein	-
STM3032	3194324..3194782	-	459	NP_461949.1	transposase for IS200	-
STM3033	3195162..3195560	-	399	NP_461950.1	putative nucleic acid-binding protein	Toxin
STM3034	3195560..3195787	-	228	NP_461951.1	putative cytoplasmic protein	Antitoxin
STM3035	3195964..3196215	+	252	NP_449411.1	putative periplasmic protein	-
STM3036	3196490..3197296	+	807	NP_461953.1	putative inner membrane protein	-
STM3038	3197581..3198339	-	759	NP_461954.1	putative metalloendopeptidase	-
STM3039	3198604..3199149	+	546	NP_461955.1	isopentenyldiphosphate isomerase	-
STM3040	3199225..3200742	-	1518	NP_461956.1	constitutive lysine tRNA synthetase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View UFRD01000002 Salmonella enterica subsp. enterica serovar Typhimurium strain NCTC12023 Genomic island TA297244 4451871..4463194 0.004 View NC_016856 Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S Genomic island TA026056 3205849..3216429 0.002 View NC_016810 Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 Genomic island TA025956 3207430..3218010 0.002 View NZ_AP023288 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-3835 Genomic island TA037173 897307..908632 0.004 View NZ_AP023289 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-3837 Genomic island TA037197 960525..971850 0.004 View NZ_AP023290 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-3844 Genomic island TA037221 879784..891109 0.004 View NZ_AP023291 Salmonella enterica subsp. enterica serovar Typhimurium strain L-4126 Genomic island TA037245 847804..859129 0.004 View NZ_AP023292 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4233 Genomic island TA037269 847808..859133 0.004 View NZ_AP023294 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4261 Genomic island TA037293 847806..859131 0.004 View NZ_AP023299 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4334 Genomic island TA037318 847808..859133 0.004 View NZ_AP023300 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4445 Genomic island TA037342 847808..859133 0.004 View NZ_AP023303 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4526 Genomic island TA037371 879784..891109 0.004 View NZ_AP023304 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4551 Genomic island TA037394 881121..892446 0.004 View NZ_AP023306 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4567 Genomic island TA037419 847808..859133 0.004 View NZ_AP023309 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4578 Genomic island TA037452 847774..859099 0.004 View NZ_AP023311 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4596 Genomic island TA037477 847808..857732 0.004 View NZ_AP023313 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4605 Genomic island TA037501 847804..859129 0.004 View NZ_AP023315 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4614 Genomic island TA037530 847782..859107 0.004 View NZ_AP023317 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4681 Genomic island TA037555 880558..891883 0.004 View NZ_AP023319 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4741 Genomic island TA037580 847808..859133 0.004 View NZ_CP047522 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF11216 Genomic island TA146346 4050921..4061501 0.002 View NZ_CP047525 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF11077 Genomic island TA146361 879809..891134 0.004 View NZ_CP047527 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10648 Genomic island TA146401 4108832..4119412 0.002 View NZ_CP047529 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10640 Genomic island TA146426 4088003..4098583 0.002 View NZ_CP047531 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10484 Genomic island TA146436 879484..890809 0.004 View NZ_CP047535 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10452 Genomic island TA146461 679513..690838 0.004 View NZ_CP047537 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10405 Genomic island TA146501 4026907..4037487 0.002 View NZ_CP047542 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10330 Genomic island TA146556 4108745..4119325 0.002 View NZ_CP047544 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10250 Genomic island TA146566 879650..890975 0.004 View NZ_CP047546 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10236 Genomic island TA146591 879605..890930 0.004 View NZ_CP047548 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10169 Genomic island TA146631 4099471..4110051 0.002 View NZ_CP047555 Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10112 Genomic island TA146688 277854..288434 0.002 View NZ_CP064385 Salmonella enterica subsp. enterica strain PartC-Senterica-RM8376 Genomic island TA181072 1931625..1942917 0 View NZ_CP067091 Salmonella enterica subsp. enterica serovar Typhimurium strain ER3625 Genomic island TA185725 3124048..3135340 0 View NZ_CP067397 Salmonella enterica subsp. enterica serovar Typhimurium strain LB5000 Genomic island TA186254 3124780..3136072 0 View NZ_CP068018 Salmonella enterica strain 1722 Genomic island TA186450 3853717..3864297 0.002 View NZ_CP068696 Salmonella enterica subsp. enterica serovar Typhimurium strain NCCP16345 Genomic island TA187603 1319973..1331298 0.004 View NZ_CP074092 Salmonella enterica subsp. enterica serovar Typhimurium strain SO_8752_Stm Genomic island TA201377 3186004..3197296 0 View NZ_CP074663 Salmonella enterica subsp. enterica serovar Typhimurium strain CFSAN008081 Genomic island TA202568 848777..860102 0.004 View NZ_CP075141 Salmonella enterica strain CFSAN033950 Genomic island TA203274 841426..852751 0.004 View NZ_CP075372 Salmonella enterica strain no75 Genomic island TA203513 929744..941069 0.004 View NZ_CP077668 Salmonella enterica strain SP Genomic island TA207381 880832..892157 0.004 View NZ_CP081187 Salmonella enterica strain sg1722-1 Genomic island TA212649 879487..890812 0.004 View NZ_CP081189 Salmonella enterica strain sg1722-2 Genomic island TA212673 879687..891012 0.004 View NZ_CP085819 Salmonella enterica subsp. enterica serovar Typhimurium strain Blastoise Genomic island TA221969 2743062..2754391 0.004 View NZ_CP085820 Salmonella enterica subsp. enterica serovar Typhimurium strain Wartortle Genomic island TA221981 843865..854445 0.002 View NZ_CP085987 Salmonella enterica strain SZL 38 Genomic island TA222427 4325888..4336468 0.002 View NZ_CP086118 Salmonella enterica subsp. enterica serovar Typhimurium strain S34 Genomic island TA222550 879684..891009 0.004 View NZ_CP088138 Salmonella enterica subsp. enterica serovar Hissar strain SCPM-O-B-4549 Genomic island TA226792 879535..890860 0.004 View NZ_CP090304 Salmonella enterica subsp. enterica serovar Typhimurium strain ZJUJY Genomic island TA230386 3186004..3197296 0 View NZ_CP090529 Salmonella enterica strain 2008079-SE Genomic island TA231017 879493..890818 0.004 View NZ_CP090533 Salmonella enterica strain 2017005-SE Genomic island TA231059 3851334..3861914 0.002 View NZ_CP090535 Salmonella enterica strain 2016089-SE Genomic island TA231071 1038411..1048991 0.002 View NZ_CP090539 Salmonella enterica strain 2016062-SE Genomic island TA231097 960309..971634 0.004 View NZ_CP090541 Salmonella enterica strain 2010112-SE Genomic island TA231122 847708..859033 0.004 View NZ_CP090545 Salmonella enterica strain 2017028-SE Genomic island TA231147 960225..971550 0.004 View NZ_CP091540 Salmonella enterica subsp. enterica serovar Typhimurium strain S46L1 Genomic island TA233573 847454..858779 0.004 View NZ_CP091542 Salmonella enterica subsp. enterica serovar Typhimurium strain S58L2 Genomic island TA233600 847699..859024 0.004 View NZ_CP091544 Salmonella enterica strain 1618 Genomic island TA233627 962756..974081 0.004 View NZ_CP091547 Salmonella enterica strain 1559 Genomic island TA233665 3852931..3863511 0.002 View NZ_CP091554 Salmonella enterica strain 751 Genomic island TA233690 3774110..3784690 0.002 View NZ_CP091556 Salmonella enterica strain 632 Genomic island TA233702 882784..894109 0.004 View NZ_CP091558 Salmonella enterica strain 418 Genomic island TA233740 3720355..3731680 0.004 View NZ_CP091560 Salmonella enterica strain 179 Genomic island TA233752 877974..889299 0.004 View NZ_CP091563 Salmonella enterica strain 143 Genomic island TA233790 3854735..3865315 0.002 View NZ_CP091566 Salmonella enterica strain 137 Genomic island TA233805 269097..280422 0.004 View NZ_CP091569 Salmonella enterica strain 131 Genomic island TA233834 880756..892081 0.004 View NZ_CP091571 Salmonella enterica strain Genomic island TA233859 879684..890628 0.003 View NZ_CP093386 Salmonella enterica strain P048595 Genomic island TA238352 848654..859979 0.004 View NZ_CP094332 Salmonella enterica subsp. enterica strain 3018683606 Genomic island TA239672 847706..859031 0.004 View NZ_CP098438 Salmonella enterica subsp. enterica serovar Typhimurium strain ATOMSal-L6 Genomic island TA247620 889478..901515 0.002 View NZ_CP098741 Salmonella enterica subsp. enterica serovar Typhimurium strain HJL222 Genomic island TA247950 1399689..1410981 0 View NZ_CP098834 Salmonella enterica subsp. enterica serovar Typhimurium strain GD19PS1 Genomic island TA248150 880107..891432 0.004 View NZ_CP099705 Salmonella enterica subsp. enterica serovar Typhimurium strain 013+ Genomic island TA249292 878077..889402 0.004 View NZ_CP100691 Salmonella enterica subsp. enterica serovar Typhimurium strain R17.3867 Genomic island TA251037 927343..938668 0.003 View NZ_CP100707 Salmonella enterica subsp. enterica serovar Typhimurium strain R18.0409 Genomic island TA251132 879723..891048 0.004 View NZ_CP100715 Salmonella enterica subsp. enterica serovar Typhimurium strain R17.5474 Genomic island TA251177 847708..859033 0.004 View NZ_CP100732 Salmonella enterica subsp. enterica serovar Typhimurium strain R18.1932 Genomic island TA251261 847680..859005 0.004 View NZ_CP100739 Salmonella enterica subsp. enterica serovar Typhimurium strain R18.0292 Genomic island TA251305 847680..859005 0.004 View NZ_CP101373 Salmonella enterica strain SC2016042 Genomic island TA251970 928446..939771 0.004 View NZ_CP101375 Salmonella enterica strain SC2016090 Genomic island TA251994 1532769..1544094 0.004 View NZ_CP101376 Salmonella enterica strain SC2016091 Genomic island TA252011 879681..891006 0.004 View NZ_CP101379 Salmonella enterica strain SC2016290 Genomic island TA252034 879681..891006 0.004 View NZ_CP101382 Salmonella enterica strain SC2017030 Genomic island TA252057 928446..939771 0.004 View NZ_CP101386 Salmonella enterica strain SC2017100 Genomic island TA252077 960422..971747 0.004 View NZ_CP101388 Salmonella enterica strain SC2017167 Genomic island TA252097 880392..891717 0.004 View NZ_CP101390 Salmonella enterica strain SC2017297 Genomic island TA252117 960414..971739 0.004 View NZ_CP102669 Salmonella enterica subsp. enterica serovar Typhimurium strain ATCC 14028 Genomic island TA253911 842290..853615 0.004 View NZ_CP104366 Salmonella enterica subsp. enterica serovar Typhimurium strain PNUSAS028809 Genomic island TA257778 847361..858686 0.004 View NZ_CP104484 Salmonella enterica strain SalSpp_sample_07_No.3 Genomic island TA258077 879568..890893 0.004 View NZ_CP110198 Salmonella enterica subsp. enterica serovar Typhimurium strain 1104-75 Genomic island TA263393 879352..890677 0.004 View NZ_CP110201 Salmonella enterica subsp. enterica serovar Typhimurium strain 1104-65 Genomic island TA263414 879552..890877 0.004 View NZ_CP110657 Salmonella enterica subsp. enterica strain S2122 Genomic island TA264086 1225282..1235862 0.002 View NZ_CP113535 Salmonella enterica strain ZLQ Genomic island TA265901 960425..971750 0.004 View NZ_CP113536 Salmonella enterica strain ZCX Genomic island TA265920 881343..892668 0.004 View NZ_CP113538 Salmonella enterica strain XSK Genomic island TA265954 877461..888786 0.004 View NZ_CP113541 Salmonella enterica strain CHC Genomic island TA266010 877577..888902 0.004 View NZ_CP116042 Salmonella enterica subsp. enterica serovar 14[5]12:i:- strain BL708 Genomic island TA267680 879453..890778 0.004 View NZ_CP117033 Salmonella enterica strain PIW95_S14_0299 Genomic island TA269883 879368..890693 0.004 View NZ_CP117184 Salmonella enterica subsp. enterica strain 123 Genomic island TA270051 3853418..3863998 0.002 View NZ_CP117244 Salmonella enterica subsp. enterica serovar Typhimurium strain ATCC 14028 Genomic island TA270171 842290..853615 0.004 View NZ_CP117338 Salmonella enterica subsp. enterica serovar Typhimurium strain RM095 Genomic island TA270610 847688..859013 0.004 View NZ_CP117357 Salmonella enterica subsp. enterica serovar Typhimurium strain RM096 Genomic island TA270766 877581..888906 0.004 View NZ_CP117370 Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain RM054 Genomic island TA270871 879676..891001 0.004 View NZ_CP117398 Salmonella enterica subsp. enterica serovar Typhimurium strain RM015 Genomic island TA271141 848949..860986 0.002 View NZ_CP117400 Salmonella enterica subsp. enterica serovar Typhimurium strain RM014 Genomic island TA271161 848949..860986 0.002 View NZ_CP117404 Salmonella enterica subsp. enterica serovar Typhimurium strain RM085 Genomic island TA271194 849165..861202 0.002 View NZ_CP121262 Salmonella enterica subsp. enterica serovar Typhimurium strain 013 Genomic island TA276142 848171..859496 0.004 View NZ_CP121298 Salmonella enterica subsp. enterica strain KKP 3080 Genomic island TA276255 1194451..1204695 0.006 View NZ_CP126138 Salmonella enterica subsp. enterica serovar Kottbus strain DSK01 Genomic island TA282656 848170..859495 0.004 View NZ_CP126325 Salmonella enterica subsp. enterica strain HL21 Genomic island TA282768 879262..892507 0.009 View NZ_OU015323 Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00004549 isolate AUSMDU00004549 Genomic island TA294627 4133482..4144807 0.004 View NZ_OU015340 Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00027944 isolate AUSMDU00027944 Genomic island TA294648 4131305..4142630 0.004 View NZ_OU015342 Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00007171 isolate AUSMDU00007171 Genomic island TA294658 879552..890877 0.004 View NC_016810 Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 Genomic island TA025956 3207430..3218010 0.002 View NC_016856 Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S Genomic island TA026056 3205849..3216429 0.002 View UFRD01000002 Salmonella enterica subsp. enterica serovar Typhimurium strain NCTC12023 Genomic island TA297244 4451871..4463194 0.004	inside	Genomic island	-	-	3186004..3197296	11292
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NZ_CP064385 Salmonella enterica subsp. enterica strain PartC-Senterica-RM8376 IS/Tn TA181072 1939945..1940403 0 View NZ_CP064385 Salmonella enterica subsp. enterica strain PartC-Senterica-RM8376 IS/Tn TA181079 3305052..3305510 0 View NZ_CP067091 Salmonella enterica subsp. enterica serovar Typhimurium strain ER3625 IS/Tn TA185725 3132368..3132826 0 View NZ_CP067091 Salmonella enterica subsp. enterica serovar Typhimurium strain ER3625 IS/Tn TA185732 4497462..4497920 0.002 View NZ_CP067397 Salmonella enterica subsp. enterica serovar Typhimurium strain LB5000 IS/Tn TA186254 3133100..3133558 0 View NZ_CP067397 Salmonella enterica subsp. enterica serovar Typhimurium strain LB5000 IS/Tn TA186261 4498192..4498650 0.002 View NZ_CP074092 Salmonella enterica subsp. enterica serovar Typhimurium strain SO_8752_Stm IS/Tn TA201377 3194324..3194782 0 View NZ_CP074092 Salmonella enterica subsp. enterica serovar Typhimurium strain SO_8752_Stm IS/Tn TA201384 4559432..4559890 0 View NZ_CP074094 Salmonella enterica subsp. enterica serovar Typhimurium strain A_cip IS/Tn TA201408 4559798..4560256 0 View NZ_CP074096 Salmonella enterica subsp. enterica serovar Typhimurium strain 2B_cip IS/Tn TA201432 4559999..4560457 0 View NZ_CP074098 Salmonella enterica subsp. enterica serovar Typhimurium strain C_cip IS/Tn TA201456 4559946..4560404 0 View NZ_CP090304 Salmonella enterica subsp. enterica serovar Typhimurium strain ZJUJY IS/Tn TA230386 3194324..3194782 0 View NZ_CP090304 Salmonella enterica subsp. enterica serovar Typhimurium strain ZJUJY IS/Tn TA230393 4559432..4559890 0 View NZ_CP098438 Salmonella enterica subsp. enterica serovar Typhimurium strain ATOMSal-L6 IS/Tn TA247632 4308414..4308872 0 View NZ_CP098438 Salmonella enterica subsp. enterica serovar Typhimurium strain ATOMSal-L6 IS/Tn TA247620 891992..892450 0 View NZ_CP098741 Salmonella enterica subsp. enterica serovar Typhimurium strain HJL222 IS/Tn TA247950 1408009..1408467 0 View NZ_CP098741 Salmonella enterica subsp. enterica serovar Typhimurium strain HJL222 IS/Tn TA247957 2773633..2774091 0 View NZ_CP117398 Salmonella enterica subsp. enterica serovar Typhimurium strain RM015 IS/Tn TA271153 4399178..4399636 0 View NZ_CP117398 Salmonella enterica subsp. enterica serovar Typhimurium strain RM015 IS/Tn TA271141 851463..851921 0 View NZ_CP117400 Salmonella enterica subsp. enterica serovar Typhimurium strain RM014 IS/Tn TA271173 4399178..4399636 0 View NZ_CP117400 Salmonella enterica subsp. enterica serovar Typhimurium strain RM014 IS/Tn TA271161 851463..851921 0 View NZ_CP117404 Salmonella enterica subsp. enterica serovar Typhimurium strain RM085 IS/Tn TA271208 4336417..4336875 0 View NZ_CP117404 Salmonella enterica subsp. enterica serovar Typhimurium strain RM085 IS/Tn TA271194 851679..852137 0 View NZ_CP121189 Salmonella enterica subsp. enterica serovar Indiana strain S1467 IS/Tn TA276022 2977158..2977616 0.005	flank	IS/Tn	-	-	3194324..3194782	458

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-123)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14938.30 Da
• Isoelectric Point: 7.2155

>T439 NP_461950.1 NC_003197:c3195560-3195162 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MLKFMLDTNTCIFTIKNKPEHIRERFNLNTSRMCISSITLMELIYGAEKSLAPERNLAVVEGFISRLEVLDYDTQAAIHT
GQIRAELARKGTPVGPYDQMIAGHAGSRGLVVVTNNLREFERIPGIRIEDWC

Nucleotide

• Length: 399 bp

>T439 NC_003197:c3195560-3195162 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTTTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8514.51 Da
• Isoelectric Point: 5.0210

>AT439 NP_461951.1 NC_003197:c3195787-3195560 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MHTTLFFSNRTQAVRLPKSISFPEDVKHVEIIAVGRSRIITPVGESWDSWFDGEGASTDFMSTREQPAVQEREGF

Nucleotide

• Length: 228 bp

>AT439 NC_003197:c3195787-3195560 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGCAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Toxin

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
T1070	Haemophilus influenzae Rd KW20	55.303	100	0.553
T4922	Actinobacillus pleuropneumoniae serovar 3 str. JL03	55.303	100	0.553
T10054	Bosea sp. PAMC 26642 strain PAMC26642	54.962	99.242	0.545
T10197	Klebsiella pneumoniae	41.667	100	0.417
T6112	uncultured bacterium	41.667	100	0.417
T6111	uncultured bacterium	41.985	99.242	0.417
T3856	Dichelobacter nodosus VCS1703A	41.221	99.242	0.409
T3858	Dichelobacter nodosus VCS1703A	41.221	99.242	0.409
T10129	Haemophilus influenzae strain 69P2H1 N69P2H1_45_2	38.462	98.485	0.379
T4914	Actinobacillus pleuropneumoniae serovar 3 str. JL03	37.5	99.225	0.372
T1066	Haemophilus influenzae Rd KW20	37.692	98.485	0.371
T652	Leptospira interrogans serovar Lai str. 56601	36.364	100	0.364
T962	Synechocystis sp. PCC 6803	39.189	89.157	0.349
T877	Sinorhizobium meliloti 1021	34.848	100	0.348

Multiple sequence alignment

Antitoxin

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
AT10054	Bosea sp. PAMC 26642 strain PAMC26642	57.333	100	0.573
AT4922	Actinobacillus pleuropneumoniae serovar 3 str. JL03	45.946	98.667	0.453
AT652	Leptospira interrogans serovar Lai str. 56601	42.105	100	0.427
AT1070	Haemophilus influenzae Rd KW20	39.474	100	0.4
AT1066	Haemophilus influenzae Rd KW20	32.5	100	0.347
AT10129	Haemophilus influenzae strain 69P2H1 N69P2H1_45_2	32.5	100	0.347
AT6112	uncultured bacterium	36.111	96	0.347
AT6111	uncultured bacterium	36.232	92	0.333
AT10197	Klebsiella pneumoniae	37.313	89.333	0.333
AT3858	Dichelobacter nodosus VCS1703A	33.333	96	0.32
AT3856	Dichelobacter nodosus VCS1703A	33.333	96	0.32

Multiple sequence alignment

References

(1) Kristoffer S Winther et al. (2009) Ectopic production of VapCs from Enterobacteria inhibits translation and trans-activates YoeB mRNA interferase. Molecular Microbiology 72(4):918-30. [PubMed:19400780]

(2) DongWon Park et al. (2020) Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca²⁺ -dependent ribonuclease. FASEB Journal : Official Publication of The Federation of American Societies For Experimental Biology 34(2):3051-3068. [PubMed:31908032]


 experimental literature
 protein structure literature