Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | yonT-as-bsrG/- |
| Location | 2219784..2220001 | Replicon | chromosome |
| Accession | NC_000964 | ||
| Organism | Bacillus subtilis subsp. subtilis str. 168 | ||
Toxin (Protein)
| Gene name | yonT | Uniprot ID | O31941 |
| Locus tag | BSU_21000 | Protein ID | NP_389983.1 |
| Coordinates | 2219784..2219960 (-) | Length | 59 a.a. |
Antitoxin (RNA)
| Gene name | as-bsrG | ||
| Locus tag | - | ||
| Coordinates | 2219901..2220001 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BSU_20950 (BSU20950) | 2214972..2215199 | - | 228 | NP_389978.1 | putative transcriptional regulator, lambda repressor-like; phage SPbeta | - |
| BSU_20960 (BSU20960) | 2215460..2216776 | - | 1317 | NP_389979.1 | conserved protein of unknown function; phage SPbeta | - |
| BSU_20970 (BSU20970) | 2217133..2217639 | - | 507 | NP_389980.1 | conserved protein of unknown function; phage SPbeta | - |
| BSU_20980 (BSU20980) | 2217967..2219199 | - | 1233 | NP_389981.1 | conserved protein of unknown function; phage SPbeta | - |
| BSU_20990 (BSU20990) | 2219281..2219469 | - | 189 | NP_389982.1 | conserved protein of unknown function; phage SPbeta | - |
| BSU_20999 (BSU20999) | 2219514..2219765 | - | 252 | YP_003097750.1 | conserved protein of unknown function (toxin/antitoxin island); phage SPbeta | - |
| BSU_21000 (BSU21000) | 2219784..2219960 | - | 177 | NP_389983.1 | toxin; phage SPbeta | Toxin |
| - | 2219901..2220001 | + | 101 | - | - | Antitoxin |
| BSU_21010 (BSU21010) | 2220335..2220946 | - | 612 | NP_389984.1 | putative hydrolase lipoprotein; phage SPbeta | - |
| BSU_21020 (BSU21020) | 2221061..2221387 | - | 327 | NP_389985.1 | putative transcriptional regulator (Xre family); phage SPbeta | - |
| BSU_21030 (BSU21030) | 2222340..2222534 | + | 195 | NP_389986.1 | hypothetical protein; phage SPbeta | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2151626..2286408 | 134782 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6882.45 Da Isoelectric Point: 12.8833
>T20252 NP_389983.1 NC_000964:c2219960-2219784 [Bacillus subtilis subsp. subtilis str. 168]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR
Download Length: 177 bp
>T20252 NC_000964:c2219960-2219784 [Bacillus subtilis subsp. subtilis str. 168]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA
Antitoxin
Download Length: 101 bp
>AT20252 NC_000964:2219901-2220001 [Bacillus subtilis subsp. subtilis str. 168]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
