Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219153..2219482 Replicon chromosome
Accession NZ_CP075344
Organism Bacillus subtilis subsp. subtilis strain A1 - Midalam

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag KIL00_RS11405 Protein ID WP_010886546.1
Coordinates 2219153..2219404 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219382..2219482 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIL00_RS11380 2214611..2214838 - 228 WP_213783396.1 helix-turn-helix transcriptional regulator -
KIL00_RS11385 2215099..2216415 - 1317 WP_004399369.1 hypothetical protein -
KIL00_RS11390 2216772..2217278 - 507 WP_004399486.1 hypothetical protein -
KIL00_RS11395 2217606..2218838 - 1233 WP_004399445.1 hypothetical protein -
KIL00_RS11400 2218920..2219108 - 189 WP_004399547.1 hypothetical protein -
KIL00_RS11405 2219153..2219404 - 252 WP_010886546.1 hypothetical protein Toxin
- 2219382..2219482 + 101 - - Antitoxin
KIL00_RS11410 2219423..2219599 - 177 WP_009967515.1 hypothetical protein -
- 2219540..2219640 + 101 NuclAT_2 - -
- 2219540..2219640 + 101 NuclAT_2 - -
- 2219540..2219640 + 101 NuclAT_2 - -
- 2219540..2219640 + 101 NuclAT_2 - -
KIL00_RS11415 2219974..2220585 - 612 WP_009967516.1 lipoprotein -
KIL00_RS11420 2220700..2221026 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
KIL00_RS11425 2221979..2222173 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151255..2286691 135436


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T203471 WP_010886546.1 NZ_CP075344:c2219404-2219153 [Bacillus subtilis subsp. subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T203471 NZ_CP100098:2024669-2024771 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 101 bp

>AT203471 NZ_CP075344:2219382-2219482 [Bacillus subtilis subsp. subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References