Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
Location | 2266895..2267185 | Replicon | chromosome |
Accession | NZ_CP050532 | ||
Organism | Bacillus subtilis subsp. subtilis str. SMY |
Toxin (Protein)
Gene name | bsrG | Uniprot ID | L8EAY0 |
Locus tag | HCN55_RS11655 | Protein ID | WP_009967548.1 |
Coordinates | 2266895..2267011 (+) | Length | 39 a.a. |
Antitoxin (RNA)
Gene name | as-bsrH | ||
Locus tag | - | ||
Coordinates | 2267006..2267185 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HCN55_RS11620 | 2262822..2262992 | - | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
HCN55_RS11625 | 2263289..2263606 | - | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
HCN55_RS11630 | 2263708..2264958 | - | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
HCN55_RS11635 | 2264951..2265283 | - | 333 | WP_004398710.1 | YolD-like family protein | - |
HCN55_RS11640 | 2265457..2265792 | + | 336 | WP_004399073.1 | hypothetical protein | - |
HCN55_RS11645 | 2265835..2266191 | - | 357 | WP_004398595.1 | hypothetical protein | - |
HCN55_RS11650 | 2266197..2266664 | - | 468 | WP_003246138.1 | YolA family protein | - |
HCN55_RS11655 | 2266895..2267011 | + | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
- | 2267006..2267185 | - | 180 | NuclAT_1 | - | Antitoxin |
- | 2267006..2267185 | - | 180 | NuclAT_1 | - | Antitoxin |
- | 2267006..2267185 | - | 180 | NuclAT_1 | - | Antitoxin |
- | 2267006..2267185 | - | 180 | NuclAT_1 | - | Antitoxin |
HCN55_RS11660 | 2267290..2267823 | - | 534 | WP_004399156.1 | GNAT family N-acetyltransferase | - |
HCN55_RS11665 | 2267859..2268437 | - | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
HCN55_RS11670 | 2268501..2268998 | - | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
HCN55_RS11675 | 2269007..2270722 | - | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
HCN55_RS11680 | 2270822..2271379 | - | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
HCN55_RS11685 | 2271463..2271648 | + | 186 | WP_003245951.1 | transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2144927..2279709 | 134782 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T153034 WP_009967548.1 NZ_CP050532:2266895-2267011 [Bacillus subtilis subsp. subtilis str. SMY]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
>T153034 NZ_CP066748:2253774-2253877 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 180 bp
>AT153034 NZ_CP050532:c2267185-2267006 [Bacillus subtilis subsp. subtilis str. SMY]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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