Detailed information of TA system
Overview
TA module
Type | I | Classification (family/domain) | yonT-as-bsrG/- |
Location | 2215015..2215232 | Replicon | chromosome |
Accession | NZ_AP019714 | ||
Organism | Bacillus subtilis subsp. subtilis strain NBRC 13719 |
Toxin (Protein)
Gene name | yonT | Uniprot ID | O31941 |
Locus tag | FNP71_RS11540 | Protein ID | WP_009967515.1 |
Coordinates | 2215015..2215191 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | as-bsrG | ||
Locus tag | - | ||
Coordinates | 2215132..2215232 (+) |
Genomic Context
Location: 2215132..2215232 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2215132..2215232 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2215132..2215232 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2215132..2215232 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2217571..2217765 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Type: Others
Protein ID: WP_004399291.1
Location: 2210203..2210430 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Type: Others
Protein ID: WP_004399298.1
Location: 2210691..2212007 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Type: Others
Protein ID: WP_004399369.1
Location: 2212364..2212870 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Type: Others
Protein ID: WP_004399486.1
Location: 2213198..2214430 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Type: Others
Protein ID: WP_004399445.1
Location: 2214512..2214700 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Type: Others
Protein ID: WP_004399547.1
Location: 2214745..2214996 (252 bp)
Type: Others
Protein ID: WP_010886546.1
Type: Others
Protein ID: WP_010886546.1
Location: 2215015..2215191 (177 bp)
Type: Toxin
Protein ID: WP_009967515.1
Type: Toxin
Protein ID: WP_009967515.1
Location: 2215566..2216177 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Type: Others
Protein ID: WP_009967516.1
Location: 2216292..2216618 (327 bp)
Type: Others
Protein ID: WP_009967517.1
Type: Others
Protein ID: WP_009967517.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FNP71_RS11510 | 2210203..2210430 | - | 228 | WP_004399298.1 | helix-turn-helix transcriptional regulator | - |
FNP71_RS11515 | 2210691..2212007 | - | 1317 | WP_004399369.1 | hypothetical protein | - |
FNP71_RS11520 | 2212364..2212870 | - | 507 | WP_004399486.1 | hypothetical protein | - |
FNP71_RS11525 | 2213198..2214430 | - | 1233 | WP_004399445.1 | hypothetical protein | - |
FNP71_RS11530 | 2214512..2214700 | - | 189 | WP_004399547.1 | hypothetical protein | - |
FNP71_RS11535 | 2214745..2214996 | - | 252 | WP_010886546.1 | hypothetical protein | - |
FNP71_RS11540 | 2215015..2215191 | - | 177 | WP_009967515.1 | hypothetical protein | Toxin |
- | 2215132..2215232 | + | 101 | NuclAT_2 | - | Antitoxin |
- | 2215132..2215232 | + | 101 | NuclAT_2 | - | Antitoxin |
- | 2215132..2215232 | + | 101 | NuclAT_2 | - | Antitoxin |
- | 2215132..2215232 | + | 101 | NuclAT_2 | - | Antitoxin |
FNP71_RS11545 | 2215566..2216177 | - | 612 | WP_009967516.1 | lipoprotein | - |
FNP71_RS11550 | 2216292..2216618 | - | 327 | WP_009967517.1 | helix-turn-helix domain-containing protein | - |
FNP71_RS11555 | 2217571..2217765 | + | 195 | WP_004399291.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2146857..2295886 | 149029 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6882.45 Da Isoelectric Point: 12.8833
>T32940 WP_009967515.1 NZ_AP019714:c2215191-2215015 [Bacillus subtilis subsp. subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR
Download Length: 177 bp
>T32940 NZ_AP019714:c2215191-2215015 [Bacillus subtilis subsp. subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA
Antitoxin
Download Length: 101 bp
>AT32940 NZ_AP019714:2215132-2215232 [Bacillus subtilis subsp. subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | O31941 |
Antitoxin
Download structure file