Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219797..2220014 Replicon chromosome
Accession NZ_CP010052
Organism Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag QU35_RS21800 Protein ID WP_009967515.1
Coordinates 2219797..2219973 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219914..2220014 (+)

Genomic Context


-----QU35_RS11015QU35_RS10980QU35_RS10985QU35_RS10990QU35_RS10995QU35_RS11000QU35_RS21795QU35_RS21800QU35_RS11005QU35_RS11010
Location: 2219914..2220014 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219914..2220014 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219914..2220014 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219914..2220014 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2222353..2222547 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Location: 2214985..2215212 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Location: 2215473..2216789 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Location: 2217146..2217652 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Location: 2217980..2219212 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Location: 2219294..2219482 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Location: 2219527..2219778 (252 bp)
Type: Others
Protein ID: WP_010886546.1
Location: 2219797..2219973 (177 bp)
Type: Toxin
Protein ID: WP_009967515.1
Location: 2220348..2220959 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Location: 2221074..2221400 (327 bp)
Type: Others
Protein ID: WP_009967517.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QU35_RS109802214985..2215212-228WP_004399298.1helix-turn-helix transcriptional regulator-
QU35_RS109852215473..2216789-1317WP_004399369.1hypothetical protein-
QU35_RS109902217146..2217652-507WP_004399486.1hypothetical protein-
QU35_RS109952217980..2219212-1233WP_004399445.1hypothetical protein-
QU35_RS110002219294..2219482-189WP_004399547.1hypothetical protein-
QU35_RS217952219527..2219778-252WP_010886546.1hypothetical protein-
QU35_RS218002219797..2219973-177WP_009967515.1hypothetical proteinToxin
-2219914..2220014+101NuclAT_2-Antitoxin
-2219914..2220014+101NuclAT_2-Antitoxin
-2219914..2220014+101NuclAT_2-Antitoxin
-2219914..2220014+101NuclAT_2-Antitoxin
QU35_RS110052220348..2220959-612WP_009967516.1lipoprotein-
QU35_RS110102221074..2221400-327WP_009967517.1helix-turn-helix domain-containing protein-
QU35_RS110152222353..2222547+195WP_004399291.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151639..2311898160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T50288 WP_009967515.1 NZ_CP010052:c2219973-2219797 [Bacillus subtilis subsp. subtilis str. 168]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T50288 NZ_CP010052:c2219973-2219797 [Bacillus subtilis subsp. subtilis str. 168]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT50288 NZ_CP010052:2219914-2220014 [Bacillus subtilis subsp. subtilis str. 168]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBO31941


Antitoxin

Download structure file

References