50288

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219797..2220014 Replicon chromosome
Accession NZ_CP010052
Organism Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag QU35_RS21800 Protein ID WP_009967515.1
Coordinates 2219797..2219973 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219914..2220014 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QU35_RS10980 2214985..2215212 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
QU35_RS10985 2215473..2216789 - 1317 WP_004399369.1 hypothetical protein -
QU35_RS10990 2217146..2217652 - 507 WP_004399486.1 hypothetical protein -
QU35_RS10995 2217980..2219212 - 1233 WP_004399445.1 hypothetical protein -
QU35_RS11000 2219294..2219482 - 189 WP_004399547.1 hypothetical protein -
QU35_RS21795 2219527..2219778 - 252 WP_010886546.1 hypothetical protein -
QU35_RS21800 2219797..2219973 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219914..2220014 + 101 NuclAT_2 - Antitoxin
- 2219914..2220014 + 101 NuclAT_2 - Antitoxin
- 2219914..2220014 + 101 NuclAT_2 - Antitoxin
- 2219914..2220014 + 101 NuclAT_2 - Antitoxin
QU35_RS11005 2220348..2220959 - 612 WP_009967516.1 lipoprotein -
QU35_RS11010 2221074..2221400 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
QU35_RS11015 2222353..2222547 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151639..2311898 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T50288 WP_009967515.1 NZ_CP010052:c2219973-2219797 [Bacillus subtilis subsp. subtilis str. 168]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T50288 NZ_CP010052:c2219973-2219797 [Bacillus subtilis subsp. subtilis str. 168]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT50288 NZ_CP010052:2219914-2220014 [Bacillus subtilis subsp. subtilis str. 168]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References