Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219202..2219419 Replicon chromosome
Accession NZ_CP103783
Organism Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag NYR92_RS11450 Protein ID WP_009967515.1
Coordinates 2219243..2219419 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219202..2219302 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR92_RS11420 2214431..2214658 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
NYR92_RS11425 2214919..2216235 - 1317 WP_004399369.1 hypothetical protein -
NYR92_RS11430 2216592..2217098 - 507 WP_004399486.1 hypothetical protein -
NYR92_RS11435 2217426..2218658 - 1233 WP_004399445.1 hypothetical protein -
NYR92_RS11440 2218740..2218928 - 189 WP_004399547.1 hypothetical protein -
NYR92_RS11445 2218973..2219224 - 252 WP_010886546.1 hypothetical protein -
- 2219202..2219302 + 101 - - Antitoxin
NYR92_RS11450 2219243..2219419 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219360..2219460 + 101 NuclAT_2 - -
- 2219360..2219460 + 101 NuclAT_2 - -
- 2219360..2219460 + 101 NuclAT_2 - -
- 2219360..2219460 + 101 NuclAT_2 - -
NYR92_RS11455 2219794..2220405 - 612 WP_009967516.1 lipoprotein -
NYR92_RS11460 2220520..2220846 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
NYR92_RS11465 2221799..2221993 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151085..2311344 160259
inside Prophage - - 2151085..2285867 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T256650 WP_009967515.1 NZ_CP103783:c2219419-2219243 [Bacillus subtilis subsp. subtilis str. 168]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

Antitoxin


Download         Length: 101 bp

>AT256650 NZ_CP103783:2219202-2219302 [Bacillus subtilis subsp. subtilis str. 168]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References