Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2200618..2200835 Replicon chromosome
Accession NZ_CP045821
Organism Bacillus subtilis strain MB8_B7

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag GII80_RS11290 Protein ID WP_009967515.1
Coordinates 2200659..2200835 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2200618..2200718 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII80_RS11260 2195847..2196074 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
GII80_RS11265 2196335..2197651 - 1317 WP_004399369.1 hypothetical protein -
GII80_RS11270 2198008..2198514 - 507 WP_004399486.1 hypothetical protein -
GII80_RS11275 2198842..2200074 - 1233 WP_004399445.1 hypothetical protein -
GII80_RS11280 2200156..2200344 - 189 WP_004399547.1 hypothetical protein -
GII80_RS11285 2200389..2200640 - 252 WP_010886546.1 hypothetical protein -
- 2200618..2200718 + 101 - - Antitoxin
GII80_RS11290 2200659..2200835 - 177 WP_009967515.1 hypothetical protein Toxin
- 2200776..2200876 + 101 NuclAT_2 - -
- 2200776..2200876 + 101 NuclAT_2 - -
- 2200776..2200876 + 101 NuclAT_2 - -
- 2200776..2200876 + 101 NuclAT_2 - -
GII80_RS11295 2201210..2201821 - 612 WP_009967516.1 lipoprotein -
GII80_RS11300 2201936..2202262 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
GII80_RS11305 2203215..2203409 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130712..2267283 136571


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T142690 WP_009967515.1 NZ_CP045821:c2200835-2200659 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T142690 NZ_CP060834:c4036514-4036230 [Salmonella enterica]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGACGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGAAGTTGTGATTGTGTTTGTTGTTGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 101 bp

>AT142690 NZ_CP045821:2200618-2200718 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References