Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2192282..2192611 Replicon chromosome
Accession NZ_CP007800
Organism Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 strain JH642

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag BSUA_RS22365 Protein ID WP_010886546.1
Coordinates 2192282..2192533 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2192511..2192611 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSUA_RS11445 2187740..2187967 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
BSUA_RS11450 2188228..2189544 - 1317 WP_004399369.1 hypothetical protein -
BSUA_RS11455 2189901..2190407 - 507 WP_004399486.1 hypothetical protein -
BSUA_RS11460 2190735..2191967 - 1233 WP_004399445.1 hypothetical protein -
BSUA_RS11465 2192049..2192237 - 189 WP_004399547.1 hypothetical protein -
BSUA_RS22365 2192282..2192533 - 252 WP_010886546.1 hypothetical protein Toxin
- 2192511..2192611 + 101 - - Antitoxin
BSUA_RS11470 2192552..2192728 - 177 WP_009967515.1 hypothetical protein -
- 2192669..2192769 + 101 NuclAT_2 - -
- 2192669..2192769 + 101 NuclAT_2 - -
- 2192669..2192769 + 101 NuclAT_2 - -
- 2192669..2192769 + 101 NuclAT_2 - -
BSUA_RS11475 2193103..2193714 - 612 WP_009967516.1 lipoprotein -
BSUA_RS11480 2193829..2194155 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
BSUA_RS11485 2195108..2195302 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2124394..2259176 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T47063 WP_010886546.1 NZ_CP007800:c2192533-2192282 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T47063 NZ_CP007800:c2192533-2192282 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT47063 NZ_CP007800:2192511-2192611 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References