Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 3466266..3466595 Replicon chromosome
Accession NZ_CP064094
Organism Bacillus subtilis strain N1108-5at

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag IRJ26_RS18445 Protein ID WP_010886546.1
Coordinates 3466344..3466595 (+) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 3466266..3466366 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ26_RS18425 3463575..3463769 - 195 WP_004399291.1 hypothetical protein -
IRJ26_RS18430 3464722..3465048 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
IRJ26_RS18435 3465163..3465774 + 612 WP_009967516.1 lipoprotein -
- 3466108..3466208 - 101 NuclAT_2 - -
- 3466108..3466208 - 101 NuclAT_2 - -
- 3466108..3466208 - 101 NuclAT_2 - -
- 3466108..3466208 - 101 NuclAT_2 - -
IRJ26_RS18440 3466149..3466325 + 177 WP_009967515.1 hypothetical protein -
- 3466266..3466366 - 101 - - Antitoxin
IRJ26_RS18445 3466344..3466595 + 252 WP_010886546.1 hypothetical protein Toxin
IRJ26_RS18450 3466640..3466828 + 189 WP_004399547.1 hypothetical protein -
IRJ26_RS18455 3466910..3468142 + 1233 WP_004399445.1 hypothetical protein -
IRJ26_RS18460 3468470..3468976 + 507 WP_004399486.1 hypothetical protein -
IRJ26_RS18465 3469333..3470649 + 1317 WP_004399369.1 hypothetical protein -
IRJ26_RS18470 3470910..3471137 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3385454..3534483 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T180070 WP_010886546.1 NZ_CP064094:3466344-3466595 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T180070 NZ_CP085060:c3563604-3563269 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 101 bp

>AT180070 NZ_CP064094:c3466366-3466266 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References