Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 3954965..3955182 Replicon chromosome
Accession NZ_CP064095
Organism Bacillus subtilis strain N1303-2Ay

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag IRJ27_RS20630 Protein ID WP_009967515.1
Coordinates 3955006..3955182 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 3954965..3955065 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ27_RS20615 (3952432) 3952432..3952626 - 195 WP_004399291.1 hypothetical protein -
IRJ27_RS20620 (3953579) 3953579..3953905 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
IRJ27_RS20625 (3954020) 3954020..3954631 + 612 WP_009967516.1 lipoprotein -
- (3954965) 3954965..3955065 - 101 NuclAT_2 - Antitoxin
- (3954965) 3954965..3955065 - 101 NuclAT_2 - Antitoxin
- (3954965) 3954965..3955065 - 101 NuclAT_2 - Antitoxin
- (3954965) 3954965..3955065 - 101 NuclAT_2 - Antitoxin
IRJ27_RS20630 (3955006) 3955006..3955182 + 177 WP_009967515.1 hypothetical protein Toxin
IRJ27_RS20635 (3955201) 3955201..3955452 + 252 WP_010886546.1 hypothetical protein -
IRJ27_RS20640 (3955497) 3955497..3955685 + 189 WP_004399547.1 hypothetical protein -
IRJ27_RS20645 (3955767) 3955767..3956999 + 1233 WP_004399445.1 hypothetical protein -
IRJ27_RS20650 (3957327) 3957327..3957833 + 507 WP_004399486.1 hypothetical protein -
IRJ27_RS20655 (3958190) 3958190..3959506 + 1317 WP_004399369.1 hypothetical protein -
IRJ27_RS20660 (3959767) 3959767..3959994 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3874311..4023340 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T180086 WP_009967515.1 NZ_CP064095:3955006-3955182 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T180086 NZ_CP085063:1041336-1041443 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 101 bp

>AT180086 NZ_CP064095:c3955065-3954965 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References