Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219350..2219567 Replicon chromosome
Accession NZ_CP065789
Organism Bacillus subtilis strain LBUM979

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag I8N71_RS11415 Protein ID WP_009967515.1
Coordinates 2219391..2219567 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219350..2219450 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I8N71_RS11385 2214579..2214806 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
I8N71_RS11390 2215067..2216383 - 1317 WP_004399369.1 hypothetical protein -
I8N71_RS11395 2216740..2217246 - 507 WP_004399486.1 hypothetical protein -
I8N71_RS11400 2217574..2218806 - 1233 WP_004399445.1 hypothetical protein -
I8N71_RS11405 2218888..2219076 - 189 WP_004399547.1 hypothetical protein -
I8N71_RS11410 2219121..2219372 - 252 WP_010886546.1 hypothetical protein -
- 2219350..2219450 + 101 - - Antitoxin
I8N71_RS11415 2219391..2219567 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219508..2219608 + 101 NuclAT_2 - -
- 2219508..2219608 + 101 NuclAT_2 - -
- 2219508..2219608 + 101 NuclAT_2 - -
- 2219508..2219608 + 101 NuclAT_2 - -
I8N71_RS11420 2219942..2220553 - 612 WP_009967516.1 lipoprotein -
I8N71_RS11425 2220668..2220994 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
I8N71_RS11430 2221947..2222141 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151233..2286015 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T183380 WP_009967515.1 NZ_CP065789:c2219567-2219391 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T183380 NZ_CP065789:c2219567-2219391 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT183380 NZ_CP065789:2219350-2219450 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References