Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219154..2219641 Replicon chromosome
Accession NZ_CP103066
Organism Bacillus subtilis strain 0137

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag NXS96_RS11455 Protein ID WP_010886546.1
Coordinates 2219154..2219405 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219541..2219641 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXS96_RS11430 (2214611) 2214611..2214838 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
NXS96_RS11435 (2215099) 2215099..2216415 - 1317 WP_004399369.1 hypothetical protein -
NXS96_RS11440 (2216772) 2216772..2217278 - 507 WP_004399486.1 hypothetical protein -
NXS96_RS11445 (2217607) 2217607..2218839 - 1233 WP_004399445.1 hypothetical protein -
NXS96_RS11450 (2218921) 2218921..2219109 - 189 WP_004399547.1 hypothetical protein -
NXS96_RS11455 (2219154) 2219154..2219405 - 252 WP_010886546.1 hypothetical protein Toxin
NXS96_RS11460 (2219424) 2219424..2219600 - 177 WP_009967515.1 hypothetical protein -
- (2219541) 2219541..2219641 + 101 NuclAT_2 - Antitoxin
- (2219541) 2219541..2219641 + 101 NuclAT_2 - Antitoxin
- (2219541) 2219541..2219641 + 101 NuclAT_2 - Antitoxin
- (2219541) 2219541..2219641 + 101 NuclAT_2 - Antitoxin
NXS96_RS11465 (2219975) 2219975..2220586 - 612 WP_009967516.1 lipoprotein -
NXS96_RS11470 (2220701) 2220701..2221027 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
NXS96_RS11475 (2221980) 2221980..2222174 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151265..2286041 134776


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T254834 WP_010886546.1 NZ_CP103066:c2219405-2219154 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp


Antitoxin


Download         Length: 101 bp

>AT254834 NZ_CP103066:2219541-2219641 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References