Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219747..2219964 Replicon chromosome
Accession NZ_CP058242
Organism Bacillus subtilis strain SP1

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag HWV68_RS11390 Protein ID WP_009967515.1
Coordinates 2219788..2219964 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219747..2219847 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWV68_RS11360 2214976..2215203 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
HWV68_RS11365 2215464..2216780 - 1317 WP_004399369.1 hypothetical protein -
HWV68_RS11370 2217137..2217643 - 507 WP_004399486.1 hypothetical protein -
HWV68_RS11375 2217971..2219203 - 1233 WP_004399445.1 hypothetical protein -
HWV68_RS11380 2219285..2219473 - 189 WP_004399547.1 hypothetical protein -
HWV68_RS11385 2219518..2219769 - 252 WP_010886546.1 hypothetical protein -
- 2219747..2219847 + 101 - - Antitoxin
HWV68_RS11390 2219788..2219964 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219905..2220005 + 101 NuclAT_2 - -
- 2219905..2220005 + 101 NuclAT_2 - -
- 2219905..2220005 + 101 NuclAT_2 - -
- 2219905..2220005 + 101 NuclAT_2 - -
HWV68_RS11395 2220339..2220950 - 612 WP_009967516.1 lipoprotein -
HWV68_RS11400 2221065..2221391 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
HWV68_RS11405 2222344..2222538 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151630..2286412 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T166387 WP_009967515.1 NZ_CP058242:c2219964-2219788 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T166387 NZ_CP074143:c1521104-1520721 [Serratia sp. JSRIV002]
ATGCAAACTGTATCGGTTACCCCGAAACGGGCAGCACCGTCTTGCCCATCACCCATCGCGATCTGGCAGGTATTGCTGAC
CCATCTATTGCAACAACACTATGGTCTGGCACTGGAAGATACCGCCTTTAGTCACGAGGGTGTGATCCAAGAGCATCTTA
ATGCAGGGATTTCCCTGGCGGATGCGCTGAATTTTATCGTGGAAAAATATGAACTGGTCCGTATTGATCGCACCGGTTTT
AGTATCCGTGAACAATCACCGTTTATTACGCCTATCGATCTTCTCCGGGCCCGACAGGCTACGGGTCTGATGAAACGCCG
AGGTTACAAGGCCATCACTCATATCACCAACGGTAAAAACCAACGACAGGGGGCACATCCGTGA

Antitoxin


Download         Length: 101 bp

>AT166387 NZ_CP058242:2219747-2219847 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References