Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2268825..2269115 Replicon chromosome
Accession NZ_AP019714
Organism Bacillus subtilis subsp. subtilis strain NBRC 13719

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag FNP71_RS11835 Protein ID WP_009967548.1
Coordinates 2268825..2268941 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2268936..2269115 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNP71_RS11800 2264752..2264922 - 171 WP_009967544.1 bacteriocin sublancin-168 -
FNP71_RS11805 2265219..2265536 - 318 WP_009967545.1 sublancin immunity protein SunI -
FNP71_RS11810 2265638..2266888 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
FNP71_RS11815 2266881..2267213 - 333 WP_004398710.1 YolD-like family protein -
FNP71_RS11820 2267387..2267722 + 336 WP_004399073.1 hypothetical protein -
FNP71_RS11825 2267765..2268121 - 357 WP_004398595.1 hypothetical protein -
FNP71_RS11830 2268127..2268594 - 468 WP_003246138.1 YolA family protein -
FNP71_RS11835 2268825..2268941 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2268936..2269115 - 180 NuclAT_1 - Antitoxin
- 2268936..2269115 - 180 NuclAT_1 - Antitoxin
- 2268936..2269115 - 180 NuclAT_1 - Antitoxin
- 2268936..2269115 - 180 NuclAT_1 - Antitoxin
FNP71_RS11840 2269220..2269753 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
FNP71_RS11845 2269789..2270367 - 579 WP_004399123.1 SMI1/KNR4 family protein -
FNP71_RS11850 2270431..2270928 - 498 WP_003246188.1 SMI1/KNR4 family protein -
FNP71_RS11855 2270937..2272652 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
FNP71_RS11860 2272752..2273309 - 558 WP_003246042.1 SMI1/KNR4 family protein -
FNP71_RS11865 2273393..2273578 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2146857..2295886 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T32944 WP_009967548.1 NZ_AP019714:2268825-2268941 [Bacillus subtilis subsp. subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T32944 NZ_AP019714:2268825-2268941 [Bacillus subtilis subsp. subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT32944 NZ_AP019714:c2269115-2268936 [Bacillus subtilis subsp. subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References