Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2936457..2936786 Replicon chromosome
Accession NZ_CP120613
Organism Bacillus subtilis strain DSM 23521

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag P5649_RS15515 Protein ID WP_010886546.1
Coordinates 2936535..2936786 (+) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2936457..2936557 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5649_RS15495 2933767..2933961 - 195 WP_004399291.1 hypothetical protein -
P5649_RS15500 2934913..2935239 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
P5649_RS15505 2935354..2935965 + 612 WP_009967516.1 lipoprotein -
- 2936299..2936399 - 101 NuclAT_2 - -
- 2936299..2936399 - 101 NuclAT_2 - -
- 2936299..2936399 - 101 NuclAT_2 - -
- 2936299..2936399 - 101 NuclAT_2 - -
P5649_RS15510 2936340..2936516 + 177 WP_009967515.1 hypothetical protein -
- 2936457..2936557 - 101 - - Antitoxin
P5649_RS15515 2936535..2936786 + 252 WP_010886546.1 hypothetical protein Toxin
P5649_RS15520 2936831..2937019 + 189 WP_004399547.1 hypothetical protein -
P5649_RS15525 2937101..2938333 + 1233 WP_004399445.1 hypothetical protein -
P5649_RS15530 2938661..2939167 + 507 WP_004399486.1 hypothetical protein -
P5649_RS15535 2939524..2940840 + 1317 WP_004399369.1 hypothetical protein -
P5649_RS15540 2941101..2941328 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2855647..3004673 149026


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T275266 WP_010886546.1 NZ_CP120613:2936535-2936786 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp


Antitoxin


Download         Length: 101 bp

>AT275266 NZ_CP120613:c2936557-2936457 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References