Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273607..2273897 Replicon chromosome
Accession NZ_CP010052
Organism Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag QU35_RS22450 Protein ID WP_009967548.1
Coordinates 2273607..2273723 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273718..2273897 (-)

Genomic Context

QU35_RS11275QU35_RS22450QU35_RS21810QU35_RS11255QU35_RS11260QU35_RS11265QU35_RS11270QU35_RS11280QU35_RS11285-----QU35_RS11290QU35_RS11295QU35_RS11300QU35_RS11305QU35_RS11310
Location: 2272169..2272504 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2273607..2273723 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2278175..2278360 (186 bp)
Type: Others
Protein ID: WP_003245951.1
Location: 2269534..2269704 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2270001..2270318 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2270420..2271670 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2271663..2271995 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2272547..2272903 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2272909..2273376 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2273718..2273897 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273718..2273897 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273718..2273897 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273718..2273897 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2274002..2274535 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2274571..2275149 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2275213..2275710 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2275719..2277434 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2277534..2278091 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QU35_RS112552269534..2269704-171WP_009967544.1bacteriocin sublancin-168-
QU35_RS112602270001..2270318-318WP_009967545.1sublancin immunity protein SunI-
QU35_RS112652270420..2271670-1251WP_004398504.1UV-damage repair protein uvrX-
QU35_RS112702271663..2271995-333WP_004398710.1YolD-like family protein-
QU35_RS112752272169..2272504+336WP_004399073.1hypothetical protein-
QU35_RS112802272547..2272903-357WP_004398595.1hypothetical protein-
QU35_RS112852272909..2273376-468WP_003246138.1YolA family protein-
QU35_RS224502273607..2273723+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2273718..2273897-180NuclAT_1-Antitoxin
-2273718..2273897-180NuclAT_1-Antitoxin
-2273718..2273897-180NuclAT_1-Antitoxin
-2273718..2273897-180NuclAT_1-Antitoxin
QU35_RS112902274002..2274535-534WP_004399156.1GNAT family N-acetyltransferase-
QU35_RS112952274571..2275149-579WP_004399123.1SMI1/KNR4 family protein-
QU35_RS113002275213..2275710-498WP_003246188.1SMI1/KNR4 family protein-
QU35_RS113052275719..2277434-1716WP_004398855.1ribonuclease YeeF family protein-
QU35_RS113102277534..2278091-558WP_003246042.1SMI1/KNR4 family protein-
QU35_RS218102278175..2278360+186WP_003245951.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151639..2311898160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T50292 WP_009967548.1 NZ_CP010052:2273607-2273723 [Bacillus subtilis subsp. subtilis str. 168]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T50292 NZ_CP010052:2273607-2273723 [Bacillus subtilis subsp. subtilis str. 168]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT50292 NZ_CP010052:c2273897-2273718 [Bacillus subtilis subsp. subtilis str. 168]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References