Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273607..2273897 Replicon chromosome
Accession NZ_CP010052
Organism Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag QU35_RS22450 Protein ID WP_009967548.1
Coordinates 2273607..2273723 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273718..2273897 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QU35_RS11255 2269534..2269704 - 171 WP_009967544.1 bacteriocin sublancin-168 -
QU35_RS11260 2270001..2270318 - 318 WP_009967545.1 sublancin immunity protein SunI -
QU35_RS11265 2270420..2271670 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
QU35_RS11270 2271663..2271995 - 333 WP_004398710.1 YolD-like family protein -
QU35_RS11275 2272169..2272504 + 336 WP_004399073.1 hypothetical protein -
QU35_RS11280 2272547..2272903 - 357 WP_004398595.1 hypothetical protein -
QU35_RS11285 2272909..2273376 - 468 WP_003246138.1 YolA family protein -
QU35_RS22450 2273607..2273723 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273718..2273897 - 180 NuclAT_1 - Antitoxin
- 2273718..2273897 - 180 NuclAT_1 - Antitoxin
- 2273718..2273897 - 180 NuclAT_1 - Antitoxin
- 2273718..2273897 - 180 NuclAT_1 - Antitoxin
QU35_RS11290 2274002..2274535 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
QU35_RS11295 2274571..2275149 - 579 WP_004399123.1 SMI1/KNR4 family protein -
QU35_RS11300 2275213..2275710 - 498 WP_003246188.1 SMI1/KNR4 family protein -
QU35_RS11305 2275719..2277434 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
QU35_RS11310 2277534..2278091 - 558 WP_003246042.1 SMI1/KNR4 family protein -
QU35_RS21810 2278175..2278360 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151639..2311898 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T50292 WP_009967548.1 NZ_CP010052:2273607-2273723 [Bacillus subtilis subsp. subtilis str. 168]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T50292 NZ_CP010052:2273607-2273723 [Bacillus subtilis subsp. subtilis str. 168]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT50292 NZ_CP010052:c2273897-2273718 [Bacillus subtilis subsp. subtilis str. 168]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References