Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrE/-
Location 2198613..2199100 Replicon chromosome
Accession NZ_CP101937
Organism Bacillus subtilis strain RUB331

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag NP435_RS11310 Protein ID WP_010886546.1
Coordinates 2198613..2198864 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2199000..2199100 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP435_RS11285 (2194071) 2194071..2194298 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
NP435_RS11290 (2194559) 2194559..2195875 - 1317 WP_004399369.1 hypothetical protein -
NP435_RS11295 (2196232) 2196232..2196738 - 507 WP_004399486.1 hypothetical protein -
NP435_RS11300 (2197066) 2197066..2198298 - 1233 WP_004399445.1 hypothetical protein -
NP435_RS11305 (2198380) 2198380..2198568 - 189 WP_004399547.1 hypothetical protein -
NP435_RS11310 (2198613) 2198613..2198864 - 252 WP_010886546.1 hypothetical protein Toxin
NP435_RS11315 (2198883) 2198883..2199059 - 177 WP_009967515.1 hypothetical protein -
- (2199000) 2199000..2199100 + 101 NuclAT_1 - Antitoxin
- (2199000) 2199000..2199100 + 101 NuclAT_1 - Antitoxin
- (2199000) 2199000..2199100 + 101 NuclAT_1 - Antitoxin
- (2199000) 2199000..2199100 + 101 NuclAT_1 - Antitoxin
NP435_RS11320 (2199434) 2199434..2200045 - 612 WP_009967516.1 lipoprotein -
NP435_RS11325 (2200160) 2200160..2200486 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
NP435_RS11330 (2201439) 2201439..2201633 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130725..2265507 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T253026 WP_010886546.1 NZ_CP101937:c2198864-2198613 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

Antitoxin


Download         Length: 101 bp

>AT253026 NZ_CP101937:2199000-2199100 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References