Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2237526..2238013 Replicon chromosome
Accession NZ_LN680001
Organism Bacillus subtilis strain BS34A

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag VV28_RS21745 Protein ID WP_010886546.1
Coordinates 2237526..2237777 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2237913..2238013 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VV28_RS10990 2232984..2233211 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
VV28_RS10995 2233472..2234788 - 1317 WP_004399369.1 hypothetical protein -
VV28_RS11000 2235145..2235651 - 507 WP_004399486.1 hypothetical protein -
VV28_RS11005 2235979..2237211 - 1233 WP_004399445.1 hypothetical protein -
VV28_RS11010 2237293..2237481 - 189 WP_004399547.1 hypothetical protein -
VV28_RS21745 2237526..2237777 - 252 WP_010886546.1 hypothetical protein Toxin
VV28_RS21750 2237796..2237972 - 177 WP_009967515.1 hypothetical protein -
- 2237913..2238013 + 101 NuclAT_2 - Antitoxin
- 2237913..2238013 + 101 NuclAT_2 - Antitoxin
- 2237913..2238013 + 101 NuclAT_2 - Antitoxin
- 2237913..2238013 + 101 NuclAT_2 - Antitoxin
VV28_RS11015 2238347..2238958 - 612 WP_009967516.1 lipoprotein -
VV28_RS11020 2239073..2239399 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
VV28_RS11025 2240352..2240546 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2169640..2305065 135425
inside Prophage - - 2169640..2304420 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T285527 WP_010886546.1 NZ_LN680001:c2237777-2237526 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

Antitoxin


Download         Length: 101 bp

>AT285527 NZ_LN680001:2237913-2238013 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References