Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2218930..2219259 Replicon chromosome
Accession NZ_CP016852
Organism Bacillus subtilis subsp. subtilis strain 168G

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag BFI33_RS22390 Protein ID WP_010886546.1
Coordinates 2218930..2219181 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219159..2219259 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFI33_RS11500 2214388..2214615 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
BFI33_RS11505 2214876..2216192 - 1317 WP_004399369.1 hypothetical protein -
BFI33_RS11510 2216549..2217055 - 507 WP_004399486.1 hypothetical protein -
BFI33_RS11515 2217383..2218615 - 1233 WP_004399445.1 hypothetical protein -
BFI33_RS11520 2218697..2218885 - 189 WP_004399547.1 hypothetical protein -
BFI33_RS22390 2218930..2219181 - 252 WP_010886546.1 hypothetical protein Toxin
- 2219159..2219259 + 101 - - Antitoxin
BFI33_RS11525 2219200..2219376 - 177 WP_009967515.1 hypothetical protein -
- 2219317..2219417 + 101 NuclAT_2 - -
- 2219317..2219417 + 101 NuclAT_2 - -
- 2219317..2219417 + 101 NuclAT_2 - -
- 2219317..2219417 + 101 NuclAT_2 - -
BFI33_RS11530 2219751..2220362 - 612 WP_009967516.1 lipoprotein -
BFI33_RS11535 2220477..2220803 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
BFI33_RS11540 2221756..2221950 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151042..2285804 134762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T65204 WP_010886546.1 NZ_CP016852:c2219181-2218930 [Bacillus subtilis subsp. subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T65204 NZ_CP016852:c2219181-2218930 [Bacillus subtilis subsp. subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT65204 NZ_CP016852:2219159-2219259 [Bacillus subtilis subsp. subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References