Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2936299..2936516 Replicon chromosome
Accession NZ_CP120613
Organism Bacillus subtilis strain DSM 23521

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag P5649_RS15510 Protein ID WP_009967515.1
Coordinates 2936340..2936516 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2936299..2936399 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5649_RS15495 (2933767) 2933767..2933961 - 195 WP_004399291.1 hypothetical protein -
P5649_RS15500 (2934913) 2934913..2935239 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
P5649_RS15505 (2935354) 2935354..2935965 + 612 WP_009967516.1 lipoprotein -
- (2936299) 2936299..2936399 - 101 NuclAT_2 - Antitoxin
- (2936299) 2936299..2936399 - 101 NuclAT_2 - Antitoxin
- (2936299) 2936299..2936399 - 101 NuclAT_2 - Antitoxin
- (2936299) 2936299..2936399 - 101 NuclAT_2 - Antitoxin
P5649_RS15510 (2936340) 2936340..2936516 + 177 WP_009967515.1 hypothetical protein Toxin
P5649_RS15515 (2936535) 2936535..2936786 + 252 WP_010886546.1 hypothetical protein -
P5649_RS15520 (2936831) 2936831..2937019 + 189 WP_004399547.1 hypothetical protein -
P5649_RS15525 (2937101) 2937101..2938333 + 1233 WP_004399445.1 hypothetical protein -
P5649_RS15530 (2938661) 2938661..2939167 + 507 WP_004399486.1 hypothetical protein -
P5649_RS15535 (2939524) 2939524..2940840 + 1317 WP_004399369.1 hypothetical protein -
P5649_RS15540 (2941101) 2941101..2941328 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2855647..3004673 149026


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T275259 WP_009967515.1 NZ_CP120613:2936340-2936516 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp


Antitoxin


Download         Length: 101 bp

>AT275259 NZ_CP120613:c2936399-2936299 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB O31941


Antitoxin

Download structure file

References