Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219354..2219571 Replicon chromosome
Accession NZ_CP125660
Organism Bacillus subtilis strain GUCC48

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag QLH41_RS11445 Protein ID WP_009967515.1
Coordinates 2219395..2219571 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219354..2219454 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH41_RS11415 2214583..2214810 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
QLH41_RS11420 2215071..2216387 - 1317 WP_004399369.1 hypothetical protein -
QLH41_RS11425 2216744..2217250 - 507 WP_004399486.1 hypothetical protein -
QLH41_RS11430 2217578..2218810 - 1233 WP_004399445.1 hypothetical protein -
QLH41_RS11435 2218892..2219080 - 189 WP_004399547.1 hypothetical protein -
QLH41_RS11440 2219125..2219376 - 252 WP_010886546.1 hypothetical protein -
- 2219354..2219454 + 101 - - Antitoxin
QLH41_RS11445 2219395..2219571 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219512..2219612 + 101 NuclAT_2 - -
- 2219512..2219612 + 101 NuclAT_2 - -
- 2219512..2219612 + 101 NuclAT_2 - -
- 2219512..2219612 + 101 NuclAT_2 - -
QLH41_RS11450 2219946..2220557 - 612 WP_009967516.1 lipoprotein -
QLH41_RS11455 2220672..2220998 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
QLH41_RS11460 2221951..2222145 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151237..2286019 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T282256 WP_009967515.1 NZ_CP125660:c2219571-2219395 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

Antitoxin


Download         Length: 101 bp

>AT282256 NZ_CP125660:2219354-2219454 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References