Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2239409..2239699 Replicon chromosome
Accession NZ_AP024624
Organism Bacillus subtilis strain BEST3106

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag K6J91_RS11525 Protein ID WP_009967548.1
Coordinates 2239409..2239525 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2239520..2239699 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J91_RS11490 (2235336) 2235336..2235506 - 171 WP_009967544.1 bacteriocin sublancin-168 -
K6J91_RS11495 (2235803) 2235803..2236120 - 318 WP_009967545.1 sublancin immunity protein SunI -
K6J91_RS11500 (2236222) 2236222..2237472 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
K6J91_RS11505 (2237465) 2237465..2237797 - 333 WP_004398710.1 YolD-like family protein -
K6J91_RS11510 (2237971) 2237971..2238306 + 336 WP_004399073.1 hypothetical protein -
K6J91_RS11515 (2238349) 2238349..2238705 - 357 WP_004398595.1 hypothetical protein -
K6J91_RS11520 (2238711) 2238711..2239178 - 468 WP_003246138.1 YolA family protein -
K6J91_RS11525 (2239409) 2239409..2239525 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2239520) 2239520..2239699 - 180 NuclAT_1 - Antitoxin
- (2239520) 2239520..2239699 - 180 NuclAT_1 - Antitoxin
- (2239520) 2239520..2239699 - 180 NuclAT_1 - Antitoxin
- (2239520) 2239520..2239699 - 180 NuclAT_1 - Antitoxin
K6J91_RS11530 (2239804) 2239804..2240337 - 534 WP_004399156.1 GNAT family protein -
K6J91_RS11535 (2240373) 2240373..2240951 - 579 WP_004399123.1 SMI1/KNR4 family protein -
K6J91_RS11540 (2241015) 2241015..2241512 - 498 WP_003246188.1 SMI1/KNR4 family protein -
K6J91_RS11545 (2241521) 2241521..2243236 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
K6J91_RS11550 (2243336) 2243336..2243893 - 558 WP_003246042.1 SMI1/KNR4 family protein -
K6J91_RS11555 (2244028) 2244028..2244162 + 135 WP_234047931.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2117443..2266470 149027


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T39045 WP_009967548.1 NZ_AP024624:2239409-2239525 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T39045 NZ_AP024624:2239409-2239525 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT39045 NZ_AP024624:c2239699-2239520 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References