142697

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2254469..2254759 Replicon chromosome
Accession NZ_CP045821
Organism Bacillus subtilis strain MB8_B7

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag GII80_RS11585 Protein ID WP_009967548.1
Coordinates 2254469..2254585 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2254580..2254759 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII80_RS11550 2250396..2250566 - 171 WP_009967544.1 bacteriocin sublancin-168 -
GII80_RS11555 2250863..2251180 - 318 WP_009967545.1 sublancin immunity protein SunI -
GII80_RS11560 2251282..2252532 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
GII80_RS11565 2252525..2252857 - 333 WP_004398710.1 YolD-like family protein -
GII80_RS11570 2253031..2253366 + 336 WP_004399073.1 hypothetical protein -
GII80_RS11575 2253409..2253765 - 357 WP_004398595.1 hypothetical protein -
GII80_RS11580 2253771..2254238 - 468 WP_003246138.1 YolA family protein -
GII80_RS11585 2254469..2254585 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2254580..2254759 - 180 NuclAT_1 - Antitoxin
- 2254580..2254759 - 180 NuclAT_1 - Antitoxin
- 2254580..2254759 - 180 NuclAT_1 - Antitoxin
- 2254580..2254759 - 180 NuclAT_1 - Antitoxin
GII80_RS11590 2254864..2255397 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
GII80_RS11595 2255433..2256011 - 579 WP_004399123.1 SMI1/KNR4 family protein -
GII80_RS11600 2256075..2256572 - 498 WP_003246188.1 SMI1/KNR4 family protein -
GII80_RS11605 2256581..2258296 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
GII80_RS11610 2258396..2258953 - 558 WP_003246042.1 SMI1/KNR4 family protein -
GII80_RS11615 2259022..2259222 + 201 WP_161793078.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130712..2267283 136571


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T142697 WP_009967548.1 NZ_CP045821:2254469-2254585 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T142697 NZ_CP060837:2036748-2036851 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 180 bp

>AT142697 NZ_CP045821:c2254759-2254580 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References