Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2253086..2253376 Replicon chromosome
Accession NZ_CP010314
Organism Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag RP72_RS23305 Protein ID WP_009967548.1
Coordinates 2253086..2253202 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2253197..2253376 (-)

Genomic Context

RP72_RS11695RP72_RS23305RP72_RS22655RP72_RS11675RP72_RS11680RP72_RS11685RP72_RS11690RP72_RS11700RP72_RS11705-----RP72_RS11715RP72_RS11720RP72_RS11725RP72_RS11730RP72_RS11735
Location: 2251648..2251983 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2253086..2253202 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2257654..2257839 (186 bp)
Type: Others
Protein ID: WP_003245951.1
Location: 2249013..2249183 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2249480..2249797 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2249899..2251149 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2251142..2251474 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2252026..2252382 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2252388..2252855 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2253197..2253376 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253197..2253376 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253197..2253376 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253197..2253376 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253481..2254014 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2254050..2254628 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2254692..2255189 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2255198..2256913 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2257013..2257570 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RP72_RS116752249013..2249183-171WP_009967544.1bacteriocin sublancin-168-
RP72_RS116802249480..2249797-318WP_009967545.1sublancin immunity protein SunI-
RP72_RS116852249899..2251149-1251WP_004398504.1UV-damage repair protein uvrX-
RP72_RS116902251142..2251474-333WP_004398710.1YolD-like family protein-
RP72_RS116952251648..2251983+336WP_004399073.1hypothetical protein-
RP72_RS117002252026..2252382-357WP_004398595.1hypothetical protein-
RP72_RS117052252388..2252855-468WP_003246138.1YolA family protein-
RP72_RS233052253086..2253202+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2253197..2253376-180NuclAT_1-Antitoxin
-2253197..2253376-180NuclAT_1-Antitoxin
-2253197..2253376-180NuclAT_1-Antitoxin
-2253197..2253376-180NuclAT_1-Antitoxin
RP72_RS117152253481..2254014-534WP_004399156.1GNAT family N-acetyltransferase-
RP72_RS117202254050..2254628-579WP_004399123.1SMI1/KNR4 family protein-
RP72_RS117252254692..2255189-498WP_003246188.1SMI1/KNR4 family protein-
RP72_RS117302255198..2256913-1716WP_004398855.1ribonuclease YeeF family protein-
RP72_RS117352257013..2257570-558WP_003246042.1SMI1/KNR4 family protein-
RP72_RS226552257654..2257839+186WP_003245951.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2131118..2265900134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T52005 WP_009967548.1 NZ_CP010314:2253086-2253202 [Bacillus subtilis subsp. subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T52005 NZ_CP010314:2253086-2253202 [Bacillus subtilis subsp. subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT52005 NZ_CP010314:c2253376-2253197 [Bacillus subtilis subsp. subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References