Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
| Location | 2253086..2253376 | Replicon | chromosome |
| Accession | NZ_CP010314 | ||
| Organism | Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet) | ||
Toxin (Protein)
| Gene name | bsrG | Uniprot ID | L8EAY0 |
| Locus tag | RP72_RS23305 | Protein ID | WP_009967548.1 |
| Coordinates | 2253086..2253202 (+) | Length | 39 a.a. |
Antitoxin (RNA)
| Gene name | as-bsrH | ||
| Locus tag | - | ||
| Coordinates | 2253197..2253376 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RP72_RS11675 | 2249013..2249183 | - | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
| RP72_RS11680 | 2249480..2249797 | - | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
| RP72_RS11685 | 2249899..2251149 | - | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
| RP72_RS11690 | 2251142..2251474 | - | 333 | WP_004398710.1 | YolD-like family protein | - |
| RP72_RS11695 | 2251648..2251983 | + | 336 | WP_004399073.1 | hypothetical protein | - |
| RP72_RS11700 | 2252026..2252382 | - | 357 | WP_004398595.1 | hypothetical protein | - |
| RP72_RS11705 | 2252388..2252855 | - | 468 | WP_003246138.1 | YolA family protein | - |
| RP72_RS23305 | 2253086..2253202 | + | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
| - | 2253197..2253376 | - | 180 | NuclAT_1 | - | Antitoxin |
| - | 2253197..2253376 | - | 180 | NuclAT_1 | - | Antitoxin |
| - | 2253197..2253376 | - | 180 | NuclAT_1 | - | Antitoxin |
| - | 2253197..2253376 | - | 180 | NuclAT_1 | - | Antitoxin |
| RP72_RS11715 | 2253481..2254014 | - | 534 | WP_004399156.1 | GNAT family N-acetyltransferase | - |
| RP72_RS11720 | 2254050..2254628 | - | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
| RP72_RS11725 | 2254692..2255189 | - | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
| RP72_RS11730 | 2255198..2256913 | - | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
| RP72_RS11735 | 2257013..2257570 | - | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
| RP72_RS22655 | 2257654..2257839 | + | 186 | WP_003245951.1 | transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2131118..2265900 | 134782 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T52005 WP_009967548.1 NZ_CP010314:2253086-2253202 [Bacillus subtilis subsp. subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
>T52005 NZ_CP010314:2253086-2253202 [Bacillus subtilis subsp. subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG
Antitoxin
Download Length: 180 bp
>AT52005 NZ_CP010314:c2253376-2253197 [Bacillus subtilis subsp. subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
