Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273223..2273513 Replicon chromosome
Accession NZ_CP032310
Organism Bacillus subtilis strain WB800N

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag D3Z87_RS11835 Protein ID WP_009967548.1
Coordinates 2273223..2273339 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273334..2273513 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3Z87_RS11800 2269150..2269320 - 171 WP_009967544.1 bacteriocin sublancin-168 -
D3Z87_RS11805 2269617..2269934 - 318 WP_009967545.1 sublancin immunity protein SunI -
D3Z87_RS11810 2270036..2271286 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
D3Z87_RS11815 2271279..2271611 - 333 WP_004398710.1 YolD-like family protein -
D3Z87_RS11820 2271785..2272120 + 336 WP_004399073.1 hypothetical protein -
D3Z87_RS11825 2272163..2272519 - 357 WP_004398595.1 hypothetical protein -
D3Z87_RS11830 2272525..2272992 - 468 WP_003246138.1 YolA family protein -
D3Z87_RS11835 2273223..2273339 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273334..2273513 - 180 NuclAT_1 - Antitoxin
- 2273334..2273513 - 180 NuclAT_1 - Antitoxin
- 2273334..2273513 - 180 NuclAT_1 - Antitoxin
- 2273334..2273513 - 180 NuclAT_1 - Antitoxin
D3Z87_RS11840 2273618..2274151 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
D3Z87_RS11845 2274187..2274765 - 579 WP_004399123.1 SMI1/KNR4 family protein -
D3Z87_RS11850 2274829..2275326 - 498 WP_003246188.1 SMI1/KNR4 family protein -
D3Z87_RS11855 2275335..2277050 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
D3Z87_RS11860 2277150..2277707 - 558 WP_003246042.1 SMI1/KNR4 family protein -
D3Z87_RS11865 2277791..2277976 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151258..2286037 134779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T111629 WP_009967548.1 NZ_CP032310:2273223-2273339 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T111629 NZ_CP032310:2273223-2273339 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT111629 NZ_CP032310:c2273513-2273334 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References