Detailed information of TA system TA180090

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 3955006..3955223
• Replicon: chromosome
• Accession: NZ_CP064095
• Organism: Bacillus subtilis strain N1303-2Ay

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: O31941
• Locus tag: IRJ27_RS20630
• Protein ID: WP_009967515.1
• Coordinates: 3955006..3955182 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	3955123..3955223 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IRJ27_RS20615	3952432..3952626	-	195	WP_004399291.1	hypothetical protein	-
IRJ27_RS20620	3953579..3953905	+	327	WP_009967517.1	helix-turn-helix transcriptional regulator	-
IRJ27_RS20625	3954020..3954631	+	612	WP_009967516.1	lipoprotein	-
-	3954965..3955065	-	101	NuclAT_2	-	-
-	3954965..3955065	-	101	NuclAT_2	-	-
-	3954965..3955065	-	101	NuclAT_2	-	-
-	3954965..3955065	-	101	NuclAT_2	-	-
IRJ27_RS20630	3955006..3955182	+	177	WP_009967515.1	hypothetical protein	Toxin
-	3955123..3955223	-	101	-	-	Antitoxin
IRJ27_RS20635	3955201..3955452	+	252	WP_010886546.1	hypothetical protein	-
IRJ27_RS20640	3955497..3955685	+	189	WP_004399547.1	hypothetical protein	-
IRJ27_RS20645	3955767..3956999	+	1233	WP_004399445.1	hypothetical protein	-
IRJ27_RS20650	3957327..3957833	+	507	WP_004399486.1	hypothetical protein	-
IRJ27_RS20655	3958190..3959506	+	1317	WP_004399369.1	hypothetical protein	-
IRJ27_RS20660	3959767..3959994	+	228	WP_004399298.1	helix-turn-helix transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_000964 Bacillus subtilis subsp. subtilis str. 168 Prophage TA006323, TA006321, TA06323b, TA020252 2151626..2286408 0.003	inside	Prophage	-	-	3874311..4023340	149029

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6882.45 Da
• Isoelectric Point: 12.8833

>T180090 WP_009967515.1 NZ_CP064095:3955006-3955182 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T180090 NZ_CP085063:c2107376-2106456 [Escherichia coli]
ATGGATCTGCGTGATAGCTATGCCCGGCAGGTCAAACTGTTGATGGCCGCTCTGCCGTATGTGGCGAAGGAGTCCTGTTT
CGCGTTGAAAGGCGGCACCGCAATCAATTTGTTTGTGCAGGATTTTCCCCGTCTGTCGGTGGATATTGATCTGGCGTATA
AGAGCTTTGCGGATCGCGATACTGATCTGGCGGCTATCAACGACGCTTTGAAGAGGATTACTGCATCGCTGAACGGCAGA
CCGGGGATCACCGCGATTCGGCAGGAAAATAAAGCGGATGAAAAGCGCATCATTGTGAATACCGCTGATGCAAAGATTAA
GATCGAGGTTAGCCCGGTCTGGCGCGGGCTGTTGTTGCCTCCGGCAGAAATGCCTGTGTGCGAACGTGTGGAAATGGAGT
ATGGCTTCACCACCATGAGTGTCGTCTCGCTGGCGGATCTTTATGGCGGTAAAATCTGCGCAGCGCTTGATCGTCAGCAC
CCGCGCGATCTGTTTGATGTGCTGAATATGCTGGAGAAACCGGGACTGATGCGGGAGATCTTTGACGGTTTTCTTTGTTA
TCTGGCAGGCCATCCCCGCCCCATTGCCGAGTTGCTGGCCCCAAACTGGGATACAGAGCGGATCACGACGCTGTATGCTC
AGGAATTTTCGGGGATGACTCAGCAGGAAACGTCGCTGGAATCGCTGCTGTCAGTAACGACTTTGCTGCCGCAGGCGTTG
AAGTCACATCTTACGGATCTGGATCGCGAGTTCTTGCTCAGTTTTAAGCAAAACAGCCCTGACTGGTCGCGGTATCGCTA
TCCTGAAATTCAGCATCTTCCGGCTATTCGCTGGAAGCAACGTAATCTGGCGGTGCTGAAAGATAAAAATCCGGCGAAGT
ATGTGGCGGCGGTGAATAAGCTAGAGAGGGTGCTGGCGTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT180090 NZ_CP064095:c3955223-3955123 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: O31941

Antitoxin