Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
| Location | 2338323..2338613 | Replicon | chromosome |
| Accession | NZ_CP015375 | ||
| Organism | Bacillus subtilis subsp. subtilis strain KCTC 3135 | ||
Toxin (Protein)
| Gene name | bsrG | Uniprot ID | L8EAY0 |
| Locus tag | AS891_RS22925 | Protein ID | WP_009967548.1 |
| Coordinates | 2338497..2338613 (-) | Length | 39 a.a. |
Antitoxin (RNA)
| Gene name | as-bsrH | ||
| Locus tag | - | ||
| Coordinates | 2338323..2338502 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AS891_RS22500 | 2333860..2334045 | - | 186 | WP_003245951.1 | transposase | - |
| AS891_RS12390 | 2334129..2334686 | + | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
| AS891_RS12395 | 2334786..2336501 | + | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
| AS891_RS12400 | 2336510..2337007 | + | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
| AS891_RS12405 | 2337071..2337649 | + | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
| AS891_RS12410 | 2337685..2338218 | + | 534 | WP_004399156.1 | GNAT family N-acetyltransferase | - |
| - | 2338323..2338502 | + | 180 | NuclAT_1 | - | Antitoxin |
| - | 2338323..2338502 | + | 180 | NuclAT_1 | - | Antitoxin |
| - | 2338323..2338502 | + | 180 | NuclAT_1 | - | Antitoxin |
| - | 2338323..2338502 | + | 180 | NuclAT_1 | - | Antitoxin |
| AS891_RS22925 | 2338497..2338613 | - | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
| AS891_RS12420 | 2338844..2339311 | + | 468 | WP_003246138.1 | YolA family protein | - |
| AS891_RS12425 | 2339317..2339673 | + | 357 | WP_004398595.1 | hypothetical protein | - |
| AS891_RS12430 | 2339716..2340051 | - | 336 | WP_004399073.1 | hypothetical protein | - |
| AS891_RS12435 | 2340225..2340557 | + | 333 | WP_004398710.1 | YolD-like family protein | - |
| AS891_RS12440 | 2340550..2341800 | + | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
| AS891_RS12445 | 2341902..2342219 | + | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
| AS891_RS12450 | 2342516..2342686 | + | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2325154..2460581 | 135427 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T62918 WP_009967548.1 NZ_CP015375:c2338613-2338497 [Bacillus subtilis subsp. subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
>T62918 NZ_CP015375:c2338613-2338497 [Bacillus subtilis subsp. subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG
Antitoxin
Download Length: 180 bp
>AT62918 NZ_CP015375:2338323-2338502 [Bacillus subtilis subsp. subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
