Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2338323..2338613 Replicon chromosome
Accession NZ_CP015375
Organism Bacillus subtilis subsp. subtilis strain KCTC 3135

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag AS891_RS22925 Protein ID WP_009967548.1
Coordinates 2338497..2338613 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2338323..2338502 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS891_RS22500 2333860..2334045 - 186 WP_003245951.1 transposase -
AS891_RS12390 2334129..2334686 + 558 WP_003246042.1 SMI1/KNR4 family protein -
AS891_RS12395 2334786..2336501 + 1716 WP_004398855.1 ribonuclease YeeF family protein -
AS891_RS12400 2336510..2337007 + 498 WP_003246188.1 SMI1/KNR4 family protein -
AS891_RS12405 2337071..2337649 + 579 WP_004399123.1 SMI1/KNR4 family protein -
AS891_RS12410 2337685..2338218 + 534 WP_004399156.1 GNAT family N-acetyltransferase -
- 2338323..2338502 + 180 NuclAT_1 - Antitoxin
- 2338323..2338502 + 180 NuclAT_1 - Antitoxin
- 2338323..2338502 + 180 NuclAT_1 - Antitoxin
- 2338323..2338502 + 180 NuclAT_1 - Antitoxin
AS891_RS22925 2338497..2338613 - 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
AS891_RS12420 2338844..2339311 + 468 WP_003246138.1 YolA family protein -
AS891_RS12425 2339317..2339673 + 357 WP_004398595.1 hypothetical protein -
AS891_RS12430 2339716..2340051 - 336 WP_004399073.1 hypothetical protein -
AS891_RS12435 2340225..2340557 + 333 WP_004398710.1 YolD-like family protein -
AS891_RS12440 2340550..2341800 + 1251 WP_004398504.1 UV-damage repair protein uvrX -
AS891_RS12445 2341902..2342219 + 318 WP_009967545.1 sublancin immunity protein SunI -
AS891_RS12450 2342516..2342686 + 171 WP_009967544.1 bacteriocin sublancin-168 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2325154..2460581 135427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T62918 WP_009967548.1 NZ_CP015375:c2338613-2338497 [Bacillus subtilis subsp. subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T62918 NZ_CP015375:c2338613-2338497 [Bacillus subtilis subsp. subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT62918 NZ_CP015375:2338323-2338502 [Bacillus subtilis subsp. subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References