Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219114..2219601 Replicon chromosome
Accession NZ_CP102769
Organism Bacillus subtilis strain YZSR384

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag NVS73_RS11440 Protein ID WP_010886546.1
Coordinates 2219114..2219365 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219501..2219601 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVS73_RS11415 (2214572) 2214572..2214799 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
NVS73_RS11420 (2215060) 2215060..2216376 - 1317 WP_004399369.1 hypothetical protein -
NVS73_RS11425 (2216733) 2216733..2217239 - 507 WP_004399486.1 hypothetical protein -
NVS73_RS11430 (2217567) 2217567..2218799 - 1233 WP_004399445.1 hypothetical protein -
NVS73_RS11435 (2218881) 2218881..2219069 - 189 WP_004399547.1 hypothetical protein -
NVS73_RS11440 (2219114) 2219114..2219365 - 252 WP_010886546.1 hypothetical protein Toxin
NVS73_RS11445 (2219384) 2219384..2219560 - 177 WP_009967515.1 hypothetical protein -
- (2219501) 2219501..2219601 + 101 NuclAT_2 - Antitoxin
- (2219501) 2219501..2219601 + 101 NuclAT_2 - Antitoxin
- (2219501) 2219501..2219601 + 101 NuclAT_2 - Antitoxin
- (2219501) 2219501..2219601 + 101 NuclAT_2 - Antitoxin
NVS73_RS11450 (2219935) 2219935..2220546 - 612 WP_009967516.1 lipoprotein -
NVS73_RS11455 (2220661) 2220661..2220987 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
NVS73_RS11460 (2221940) 2221940..2222134 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151226..2286008 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T254169 WP_010886546.1 NZ_CP102769:c2219365-2219114 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

Antitoxin


Download         Length: 101 bp

>AT254169 NZ_CP102769:2219501-2219601 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References