Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273227..2273517 Replicon chromosome
Accession NZ_CP103066
Organism Bacillus subtilis strain 0137

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag NXS96_RS11755 Protein ID WP_009967548.1
Coordinates 2273227..2273343 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273338..2273517 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXS96_RS11720 (2269158) 2269158..2269328 - 171 WP_009967544.1 bacteriocin sublancin-168 -
NXS96_RS11725 (2269625) 2269625..2269942 - 318 WP_009967545.1 sublancin immunity protein SunI -
NXS96_RS11730 (2270044) 2270044..2271290 - 1247 Protein_2259 UV damage repair protein UvrX -
NXS96_RS11735 (2271283) 2271283..2271615 - 333 WP_004398710.1 YolD-like family protein -
NXS96_RS11740 (2271789) 2271789..2272124 + 336 WP_004399073.1 hypothetical protein -
NXS96_RS11745 (2272167) 2272167..2272523 - 357 WP_004398595.1 hypothetical protein -
NXS96_RS11750 (2272529) 2272529..2272996 - 468 WP_003246138.1 YolA family protein -
NXS96_RS11755 (2273227) 2273227..2273343 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2273338) 2273338..2273517 - 180 NuclAT_1 - Antitoxin
- (2273338) 2273338..2273517 - 180 NuclAT_1 - Antitoxin
- (2273338) 2273338..2273517 - 180 NuclAT_1 - Antitoxin
- (2273338) 2273338..2273517 - 180 NuclAT_1 - Antitoxin
NXS96_RS11760 (2273622) 2273622..2274155 - 534 WP_004399156.1 GNAT family protein -
NXS96_RS11765 (2274191) 2274191..2274769 - 579 WP_004399123.1 SMI1/KNR4 family protein -
NXS96_RS11770 (2274833) 2274833..2275330 - 498 WP_003246188.1 SMI1/KNR4 family protein -
NXS96_RS11775 (2275339) 2275339..2277054 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
NXS96_RS11780 (2277154) 2277154..2277711 - 558 WP_003246042.1 SMI1/KNR4 family protein -
NXS96_RS11785 (2277846) 2277846..2277980 + 135 WP_234047931.1 transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151265..2286041 134776


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-38)


Sequences


Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T254841 WP_009967548.1 NZ_CP103066:2273227-2273343 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp


Antitoxin


Download         Length: 180 bp

>AT254841 NZ_CP103066:c2273517-2273338 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9


Antitoxin

Download structure file

References