Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2291604..2291894 Replicon chromosome
Accession NZ_LN649259
Organism Bacillus subtilis strain BS49

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag VV34_RS23645 Protein ID WP_009967548.1
Coordinates 2291604..2291720 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2291715..2291894 (-)

Genomic Context

VV34_RS11885VV34_RS23645VV34_RS22950VV34_RS11865VV34_RS11870VV34_RS11875VV34_RS11880VV34_RS11890VV34_RS11895-----VV34_RS11905VV34_RS11910VV34_RS11915VV34_RS11920VV34_RS11925
Location: 2290166..2290501 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2291604..2291720 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2296157..2296357 (201 bp)
Type: Others
Protein ID: WP_161793078.1
Location: 2287531..2287701 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2287998..2288315 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2288417..2289667 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2289660..2289992 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2290544..2290900 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2290906..2291373 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2291715..2291894 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2291715..2291894 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2291715..2291894 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2291715..2291894 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2291999..2292532 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2292568..2293146 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2293210..2293707 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2293716..2295431 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2295531..2296088 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VV34_RS118652287531..2287701-171WP_009967544.1bacteriocin sublancin-168-
VV34_RS118702287998..2288315-318WP_009967545.1sublancin immunity protein SunI-
VV34_RS118752288417..2289667-1251WP_004398504.1UV-damage repair protein uvrX-
VV34_RS118802289660..2289992-333WP_004398710.1YolD-like family protein-
VV34_RS118852290166..2290501+336WP_004399073.1hypothetical protein-
VV34_RS118902290544..2290900-357WP_004398595.1hypothetical protein-
VV34_RS118952290906..2291373-468WP_003246138.1YolA family protein-
VV34_RS236452291604..2291720+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2291715..2291894-180NuclAT_1-Antitoxin
-2291715..2291894-180NuclAT_1-Antitoxin
-2291715..2291894-180NuclAT_1-Antitoxin
-2291715..2291894-180NuclAT_1-Antitoxin
VV34_RS119052291999..2292532-534WP_004399156.1GNAT family N-acetyltransferase-
VV34_RS119102292568..2293146-579WP_004399123.1SMI1/KNR4 family protein-
VV34_RS119152293210..2293707-498WP_003246188.1SMI1/KNR4 family protein-
VV34_RS119202293716..2295431-1716WP_004398855.1ribonuclease YeeF family protein-
VV34_RS119252295531..2296088-558WP_003246042.1SMI1/KNR4 family protein-
VV34_RS229502296157..2296357+201WP_161793078.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2169638..2304418134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T285513 WP_009967548.1 NZ_LN649259:2291604-2291720 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

Antitoxin


Download         Length: 180 bp

>AT285513 NZ_LN649259:c2291894-2291715 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References