Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2192282..2192611 Replicon chromosome
Accession NZ_CP008698
Organism Bacillus subtilis subsp. subtilis str. AG1839

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag BSUB_RS22380 Protein ID WP_010886546.1
Coordinates 2192282..2192533 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2192511..2192611 (+)

Genomic Context


------BSUB_RS11480BSUB_RS11440BSUB_RS11445BSUB_RS11450BSUB_RS11455BSUB_RS11460BSUB_RS22380BSUB_RS11465BSUB_RS11470BSUB_RS11475
Location: 2192511..2192611 (101 bp)
Type: Antitoxin
Protein ID: -
Location: 2192669..2192769 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2192669..2192769 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2192669..2192769 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2192669..2192769 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2195108..2195302 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Location: 2187740..2187967 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Location: 2188228..2189544 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Location: 2189901..2190407 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Location: 2190735..2191967 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Location: 2192049..2192237 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Location: 2192282..2192533 (252 bp)
Type: Toxin
Protein ID: WP_010886546.1
Location: 2192552..2192728 (177 bp)
Type: Others
Protein ID: WP_009967515.1
Location: 2193103..2193714 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Location: 2193829..2194155 (327 bp)
Type: Others
Protein ID: WP_009967517.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BSUB_RS114402187740..2187967-228WP_004399298.1helix-turn-helix transcriptional regulator-
BSUB_RS114452188228..2189544-1317WP_004399369.1hypothetical protein-
BSUB_RS114502189901..2190407-507WP_004399486.1hypothetical protein-
BSUB_RS114552190735..2191967-1233WP_004399445.1hypothetical protein-
BSUB_RS114602192049..2192237-189WP_004399547.1hypothetical protein-
BSUB_RS223802192282..2192533-252WP_010886546.1hypothetical proteinToxin
-2192511..2192611+101--Antitoxin
BSUB_RS114652192552..2192728-177WP_009967515.1hypothetical protein-
-2192669..2192769+101NuclAT_2--
-2192669..2192769+101NuclAT_2--
-2192669..2192769+101NuclAT_2--
-2192669..2192769+101NuclAT_2--
BSUB_RS114702193103..2193714-612WP_009967516.1lipoprotein-
BSUB_RS114752193829..2194155-327WP_009967517.1helix-turn-helix domain-containing protein-
BSUB_RS114802195108..2195302+195WP_004399291.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2124394..2259176134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-48)


Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T47257 WP_010886546.1 NZ_CP008698:c2192533-2192282 [Bacillus subtilis subsp. subtilis str. AG1839]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T47257 NZ_CP008698:c2192533-2192282 [Bacillus subtilis subsp. subtilis str. AG1839]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT47257 NZ_CP008698:2192511-2192611 [Bacillus subtilis subsp. subtilis str. AG1839]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBC0H439


Antitoxin

Download structure file

References