50315

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273354..2273644 Replicon chromosome
Accession NZ_CP010053
Organism Bacillus subtilis strain PS832

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag QX56_RS22430 Protein ID WP_009967548.1
Coordinates 2273354..2273470 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273465..2273644 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QX56_RS11230 2269281..2269451 - 171 WP_009967544.1 bacteriocin sublancin-168 -
QX56_RS11235 2269748..2270065 - 318 WP_009967545.1 sublancin immunity protein SunI -
QX56_RS11240 2270167..2271417 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
QX56_RS11245 2271410..2271742 - 333 WP_004398710.1 YolD-like family protein -
QX56_RS11250 2271916..2272251 + 336 WP_004399073.1 hypothetical protein -
QX56_RS11255 2272294..2272650 - 357 WP_004398595.1 hypothetical protein -
QX56_RS11260 2272656..2273123 - 468 WP_003246138.1 YolA family protein -
QX56_RS22430 2273354..2273470 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273465..2273644 - 180 NuclAT_1 - Antitoxin
- 2273465..2273644 - 180 NuclAT_1 - Antitoxin
- 2273465..2273644 - 180 NuclAT_1 - Antitoxin
- 2273465..2273644 - 180 NuclAT_1 - Antitoxin
QX56_RS11265 2273749..2274282 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
QX56_RS11270 2274318..2274896 - 579 WP_004399123.1 SMI1/KNR4 family protein -
QX56_RS11275 2274960..2275457 - 498 WP_003246188.1 SMI1/KNR4 family protein -
QX56_RS11280 2275466..2277181 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
QX56_RS11285 2277281..2277838 - 558 WP_003246042.1 SMI1/KNR4 family protein -
QX56_RS21780 2277922..2278107 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151386..2286168 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T50315 WP_009967548.1 NZ_CP010053:2273354-2273470 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T50315 NZ_CP010053:2273354-2273470 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT50315 NZ_CP010053:c2273644-2273465 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References