Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2185577..2185794 Replicon chromosome
Accession NZ_AP024626
Organism Bacillus subtilis strain BEST3125

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K6K02_RS11195 Protein ID WP_009967515.1
Coordinates 2185618..2185794 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2185577..2185677 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K02_RS11165 2180806..2181033 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6K02_RS11170 2181294..2182610 - 1317 WP_004399369.1 hypothetical protein -
K6K02_RS11175 2182967..2183473 - 507 WP_004399486.1 hypothetical protein -
K6K02_RS11180 2183801..2185033 - 1233 WP_004399445.1 hypothetical protein -
K6K02_RS11185 2185115..2185303 - 189 WP_004399547.1 hypothetical protein -
K6K02_RS11190 2185348..2185599 - 252 WP_010886546.1 hypothetical protein -
- 2185577..2185677 + 101 - - Antitoxin
K6K02_RS11195 2185618..2185794 - 177 WP_009967515.1 hypothetical protein Toxin
- 2185735..2185835 + 101 NuclAT_2 - -
- 2185735..2185835 + 101 NuclAT_2 - -
- 2185735..2185835 + 101 NuclAT_2 - -
- 2185735..2185835 + 101 NuclAT_2 - -
K6K02_RS11200 2186169..2186780 - 612 WP_009967516.1 lipoprotein -
K6K02_RS11205 2186895..2187221 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6K02_RS11210 2188174..2188368 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2117462..2266489 149027


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T39084 WP_009967515.1 NZ_AP024626:c2185794-2185618 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T39084 NZ_AP024626:c2185794-2185618 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT39084 NZ_AP024626:2185577-2185677 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References