Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2272990..2273280 Replicon chromosome
Accession NZ_CP016852
Organism Bacillus subtilis subsp. subtilis strain 168G

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag BFI33_RS22815 Protein ID WP_009967548.1
Coordinates 2272990..2273106 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273101..2273280 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFI33_RS11780 2268937..2269107 - 171 WP_009967544.1 bacteriocin sublancin-168 -
BFI33_RS11785 2269385..2269702 - 318 WP_009967545.1 sublancin immunity protein SunI -
BFI33_RS11790 2269804..2271053 - 1250 Protein_2246 UV damage repair protein UvrX -
BFI33_RS11795 2271046..2271378 - 333 WP_004398710.1 YolD-like family protein -
BFI33_RS11800 2271552..2271887 + 336 WP_004399073.1 hypothetical protein -
BFI33_RS11805 2271930..2272286 - 357 WP_004398595.1 hypothetical protein -
BFI33_RS11810 2272292..2272759 - 468 WP_003246138.1 YolA family protein -
BFI33_RS22815 2272990..2273106 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273101..2273280 - 180 NuclAT_1 - Antitoxin
- 2273101..2273280 - 180 NuclAT_1 - Antitoxin
- 2273101..2273280 - 180 NuclAT_1 - Antitoxin
- 2273101..2273280 - 180 NuclAT_1 - Antitoxin
BFI33_RS11820 2273385..2273918 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
BFI33_RS11825 2273954..2274532 - 579 WP_004399123.1 SMI1/KNR4 family protein -
BFI33_RS11830 2274596..2275093 - 498 WP_003246188.1 SMI1/KNR4 family protein -
BFI33_RS11835 2275102..2276817 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
BFI33_RS11840 2276917..2277474 - 558 WP_003246042.1 SMI1/KNR4 family protein -
BFI33_RS22395 2277558..2277743 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151042..2285804 134762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T65214 WP_009967548.1 NZ_CP016852:2272990-2273106 [Bacillus subtilis subsp. subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T65214 NZ_CP016852:2272990-2273106 [Bacillus subtilis subsp. subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT65214 NZ_CP016852:c2273280-2273101 [Bacillus subtilis subsp. subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References