Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219106..2219435 Replicon chromosome
Accession NZ_CP045812
Organism Bacillus subtilis strain P8_B3

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag GII89_RS11400 Protein ID WP_010886546.1
Coordinates 2219106..2219357 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219335..2219435 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII89_RS11375 2214564..2214791 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
GII89_RS11380 2215052..2216368 - 1317 WP_004399369.1 hypothetical protein -
GII89_RS11385 2216725..2217231 - 507 WP_004399486.1 hypothetical protein -
GII89_RS11390 2217559..2218791 - 1233 WP_004399445.1 hypothetical protein -
GII89_RS11395 2218873..2219061 - 189 WP_004399547.1 hypothetical protein -
GII89_RS11400 2219106..2219357 - 252 WP_010886546.1 hypothetical protein Toxin
- 2219335..2219435 + 101 - - Antitoxin
GII89_RS11405 2219376..2219552 - 177 WP_009967515.1 hypothetical protein -
- 2219493..2219593 + 101 NuclAT_2 - -
- 2219493..2219593 + 101 NuclAT_2 - -
- 2219493..2219593 + 101 NuclAT_2 - -
- 2219493..2219593 + 101 NuclAT_2 - -
GII89_RS11410 2219927..2220538 - 612 WP_009967516.1 lipoprotein -
GII89_RS11415 2220653..2220979 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
GII89_RS11420 2221932..2222126 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151218..2286000 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T142634 WP_010886546.1 NZ_CP045812:c2219357-2219106 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T142634 NZ_CP060796:2654227-2654370 [Enterococcus faecalis]
ATGAATGTAAGTGCTAAAATCTATGAAAGGAGAGGCCTTTTGTCAGCATATGAGACAATTCAGACGATTCTAGGTTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 101 bp

>AT142634 NZ_CP045812:2219335-2219435 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References