Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273201..2273491 Replicon chromosome
Accession NZ_CP065789
Organism Bacillus subtilis strain LBUM979

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag I8N71_RS11710 Protein ID WP_009967548.1
Coordinates 2273201..2273317 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273312..2273491 (-)

Genomic Context

I8N71_RS11695I8N71_RS11710I8N71_RS11740I8N71_RS11675I8N71_RS11680I8N71_RS11685I8N71_RS11690I8N71_RS11700I8N71_RS11705-----I8N71_RS11715I8N71_RS11720I8N71_RS11725I8N71_RS11730I8N71_RS11735
Location: 2271763..2272098 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2273201..2273317 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2277769..2277954 (186 bp)
Type: Others
Protein ID: WP_003245951.1
Location: 2269128..2269298 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2269595..2269912 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2270014..2271264 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2271257..2271589 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2272141..2272497 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2272503..2272970 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2273312..2273491 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273312..2273491 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273312..2273491 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273312..2273491 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273596..2274129 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2274165..2274743 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2274807..2275304 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2275313..2277028 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2277128..2277685 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I8N71_RS116752269128..2269298-171WP_009967544.1bacteriocin sublancin-168-
I8N71_RS116802269595..2269912-318WP_009967545.1sublancin immunity protein SunI-
I8N71_RS116852270014..2271264-1251WP_004398504.1UV-damage repair protein uvrX-
I8N71_RS116902271257..2271589-333WP_004398710.1YolD-like family protein-
I8N71_RS116952271763..2272098+336WP_004399073.1hypothetical protein-
I8N71_RS117002272141..2272497-357WP_004398595.1hypothetical protein-
I8N71_RS117052272503..2272970-468WP_003246138.1YolA family protein-
I8N71_RS117102273201..2273317+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2273312..2273491-180NuclAT_1-Antitoxin
-2273312..2273491-180NuclAT_1-Antitoxin
-2273312..2273491-180NuclAT_1-Antitoxin
-2273312..2273491-180NuclAT_1-Antitoxin
I8N71_RS117152273596..2274129-534WP_004399156.1GNAT family N-acetyltransferase-
I8N71_RS117202274165..2274743-579WP_004399123.1SMI1/KNR4 family protein-
I8N71_RS117252274807..2275304-498WP_003246188.1SMI1/KNR4 family protein-
I8N71_RS117302275313..2277028-1716WP_004398855.1ribonuclease YeeF family protein-
I8N71_RS117352277128..2277685-558WP_003246042.1SMI1/KNR4 family protein-
I8N71_RS117402277769..2277954+186WP_003245951.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151233..2286015134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T183387 WP_009967548.1 NZ_CP065789:2273201-2273317 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T183387 NZ_CP086956:115052-115303 [Pseudosulfitobacter pseudonitzschiae]
ATGGATGTTATGACCTATTCAGACGCACGAGCTCAACTGAAGGGCGTCATGGATCGAGCGATCCACGACAAGCAAGAAGT
TGTTGTGACGCGCAAAAAAGGAGAGTCCGTCGTGGTCGTATCCTTGGAAACCTGGAACGCCGTAAATGAGACGCTGCACC
TCCTGTCCACACCAAAAAACGCATCCCGCTTGCGCGCGTCGATCGCGCAACTCGATGCTGGAACTGGCGAAGTGCGTGAG
CTGACCGAGTGA

Antitoxin


Download         Length: 180 bp

>AT183387 NZ_CP065789:c2273491-2273312 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References