Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273201..2273491 Replicon chromosome
Accession NZ_CP065789
Organism Bacillus subtilis strain LBUM979

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag I8N71_RS11710 Protein ID WP_009967548.1
Coordinates 2273201..2273317 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273312..2273491 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I8N71_RS11675 2269128..2269298 - 171 WP_009967544.1 bacteriocin sublancin-168 -
I8N71_RS11680 2269595..2269912 - 318 WP_009967545.1 sublancin immunity protein SunI -
I8N71_RS11685 2270014..2271264 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
I8N71_RS11690 2271257..2271589 - 333 WP_004398710.1 YolD-like family protein -
I8N71_RS11695 2271763..2272098 + 336 WP_004399073.1 hypothetical protein -
I8N71_RS11700 2272141..2272497 - 357 WP_004398595.1 hypothetical protein -
I8N71_RS11705 2272503..2272970 - 468 WP_003246138.1 YolA family protein -
I8N71_RS11710 2273201..2273317 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273312..2273491 - 180 NuclAT_1 - Antitoxin
- 2273312..2273491 - 180 NuclAT_1 - Antitoxin
- 2273312..2273491 - 180 NuclAT_1 - Antitoxin
- 2273312..2273491 - 180 NuclAT_1 - Antitoxin
I8N71_RS11715 2273596..2274129 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
I8N71_RS11720 2274165..2274743 - 579 WP_004399123.1 SMI1/KNR4 family protein -
I8N71_RS11725 2274807..2275304 - 498 WP_003246188.1 SMI1/KNR4 family protein -
I8N71_RS11730 2275313..2277028 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
I8N71_RS11735 2277128..2277685 - 558 WP_003246042.1 SMI1/KNR4 family protein -
I8N71_RS11740 2277769..2277954 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151233..2286015 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T183387 WP_009967548.1 NZ_CP065789:2273201-2273317 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T183387 NZ_CP086956:115052-115303 [Pseudosulfitobacter pseudonitzschiae]
ATGGATGTTATGACCTATTCAGACGCACGAGCTCAACTGAAGGGCGTCATGGATCGAGCGATCCACGACAAGCAAGAAGT
TGTTGTGACGCGCAAAAAAGGAGAGTCCGTCGTGGTCGTATCCTTGGAAACCTGGAACGCCGTAAATGAGACGCTGCACC
TCCTGTCCACACCAAAAAACGCATCCCGCTTGCGCGCGTCGATCGCGCAACTCGATGCTGGAACTGGCGAAGTGCGTGAG
CTGACCGAGTGA

Antitoxin


Download         Length: 180 bp

>AT183387 NZ_CP065789:c2273491-2273312 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References