Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2253209..2253499 Replicon chromosome
Accession NZ_CP015004
Organism Bacillus subtilis strain SZMC 6179J isolate B23

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag A3772_RS22700 Protein ID WP_009967548.1
Coordinates 2253209..2253325 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2253320..2253499 (-)

Genomic Context

A3772_RS11680A3772_RS22700A3772_RS22265A3772_RS11660A3772_RS11665A3772_RS11670A3772_RS11675A3772_RS11685A3772_RS11690-----A3772_RS11700A3772_RS11705A3772_RS11710A3772_RS11715A3772_RS11720
Location: 2251771..2252106 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2253209..2253325 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2257777..2257962 (186 bp)
Type: Others
Protein ID: WP_003245951.1
Location: 2249136..2249306 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2249603..2249920 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2250022..2251272 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2251265..2251597 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2252149..2252505 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2252511..2252978 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2253320..2253499 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253320..2253499 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253320..2253499 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253320..2253499 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2253604..2254137 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2254173..2254751 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2254815..2255312 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2255321..2257036 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2257136..2257693 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A3772_RS116602249136..2249306-171WP_009967544.1bacteriocin sublancin-168-
A3772_RS116652249603..2249920-318WP_009967545.1sublancin immunity protein SunI-
A3772_RS116702250022..2251272-1251WP_004398504.1UV-damage repair protein uvrX-
A3772_RS116752251265..2251597-333WP_004398710.1YolD-like family protein-
A3772_RS116802251771..2252106+336WP_004399073.1hypothetical protein-
A3772_RS116852252149..2252505-357WP_004398595.1hypothetical protein-
A3772_RS116902252511..2252978-468WP_003246138.1YolA family protein-
A3772_RS227002253209..2253325+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2253320..2253499-180NuclAT_1-Antitoxin
-2253320..2253499-180NuclAT_1-Antitoxin
-2253320..2253499-180NuclAT_1-Antitoxin
-2253320..2253499-180NuclAT_1-Antitoxin
A3772_RS117002253604..2254137-534WP_004399156.1GNAT family N-acetyltransferase-
A3772_RS117052254173..2254751-579WP_004399123.1SMI1/KNR4 family protein-
A3772_RS117102254815..2255312-498WP_003246188.1SMI1/KNR4 family protein-
A3772_RS117152255321..2257036-1716WP_004398855.1ribonuclease YeeF family protein-
A3772_RS117202257136..2257693-558WP_003246042.1SMI1/KNR4 family protein-
A3772_RS222652257777..2257962+186WP_003245951.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2131241..2266023134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T62014 WP_009967548.1 NZ_CP015004:2253209-2253325 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T62014 NZ_CP015004:2253209-2253325 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT62014 NZ_CP015004:c2253499-2253320 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References