Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 1419329..1419546 Replicon chromosome
Accession NZ_CP064096
Organism Bacillus subtilis strain N1142-3at

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag IRJ28_RS07680 Protein ID WP_009967515.1
Coordinates 1419370..1419546 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 1419329..1419429 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ28_RS07665 (1416796) 1416796..1416990 - 195 WP_004399291.1 hypothetical protein -
IRJ28_RS07670 (1417943) 1417943..1418269 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
IRJ28_RS07675 (1418384) 1418384..1418995 + 612 WP_009967516.1 lipoprotein -
- (1419329) 1419329..1419429 - 101 NuclAT_2 - Antitoxin
- (1419329) 1419329..1419429 - 101 NuclAT_2 - Antitoxin
- (1419329) 1419329..1419429 - 101 NuclAT_2 - Antitoxin
- (1419329) 1419329..1419429 - 101 NuclAT_2 - Antitoxin
IRJ28_RS07680 (1419370) 1419370..1419546 + 177 WP_009967515.1 hypothetical protein Toxin
IRJ28_RS07685 (1419565) 1419565..1419816 + 252 WP_010886546.1 hypothetical protein -
IRJ28_RS07690 (1419861) 1419861..1420049 + 189 WP_004399547.1 hypothetical protein -
IRJ28_RS07695 (1420131) 1420131..1421363 + 1233 WP_004399445.1 hypothetical protein -
IRJ28_RS07700 (1421691) 1421691..1422197 + 507 WP_004399486.1 hypothetical protein -
IRJ28_RS07705 (1422554) 1422554..1423870 + 1317 WP_004399369.1 hypothetical protein -
IRJ28_RS07710 (1424131) 1424131..1424358 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1327445..1487704 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T180107 WP_009967515.1 NZ_CP064096:1419370-1419546 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T180107 NZ_CP085064:c121575-121270 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 101 bp

>AT180107 NZ_CP064096:c1419429-1419329 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References