Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 3412225..3412515 Replicon chromosome
Accession NZ_CP064094
Organism Bacillus subtilis strain N1108-5at

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag IRJ26_RS18145 Protein ID WP_009967548.1
Coordinates 3412399..3412515 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 3412225..3412404 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ26_RS18115 (3407762) 3407762..3407896 - 135 WP_234047931.1 transposase -
IRJ26_RS18120 (3408031) 3408031..3408588 + 558 WP_003246042.1 SMI1/KNR4 family protein -
IRJ26_RS18125 (3408688) 3408688..3410403 + 1716 WP_004398855.1 ribonuclease YeeF family protein -
IRJ26_RS18130 (3410412) 3410412..3410909 + 498 WP_003246188.1 SMI1/KNR4 family protein -
IRJ26_RS18135 (3410973) 3410973..3411551 + 579 WP_004399123.1 SMI1/KNR4 family protein -
IRJ26_RS18140 (3411587) 3411587..3412120 + 534 WP_004399156.1 GNAT family protein -
- (3412225) 3412225..3412404 + 180 NuclAT_1 - Antitoxin
- (3412225) 3412225..3412404 + 180 NuclAT_1 - Antitoxin
- (3412225) 3412225..3412404 + 180 NuclAT_1 - Antitoxin
- (3412225) 3412225..3412404 + 180 NuclAT_1 - Antitoxin
IRJ26_RS18145 (3412399) 3412399..3412515 - 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
IRJ26_RS18150 (3412746) 3412746..3413213 + 468 WP_003246138.1 YolA family protein -
IRJ26_RS18155 (3413219) 3413219..3413575 + 357 WP_004398595.1 hypothetical protein -
IRJ26_RS18160 (3413618) 3413618..3413953 - 336 WP_004399073.1 hypothetical protein -
IRJ26_RS18165 (3414127) 3414127..3414459 + 333 WP_004398710.1 YolD-like family protein -
IRJ26_RS18170 (3414452) 3414452..3415702 + 1251 WP_004398504.1 UV-damage repair protein uvrX -
IRJ26_RS18175 (3415804) 3415804..3416121 + 318 WP_009967545.1 sublancin immunity protein SunI -
IRJ26_RS18180 (3416418) 3416418..3416588 + 171 WP_009967544.1 bacteriocin sublancin-168 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3385454..3534483 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T180059 WP_009967548.1 NZ_CP064094:c3412515-3412399 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T180059 NZ_CP085060:c1086711-1086493 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 180 bp

>AT180059 NZ_CP064094:3412225-3412404 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References