39041

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2185599..2185816 Replicon chromosome
Accession NZ_AP024624
Organism Bacillus subtilis strain BEST3106

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K6J91_RS11230 Protein ID WP_009967515.1
Coordinates 2185599..2185775 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2185716..2185816 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J91_RS11200 (2180787) 2180787..2181014 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6J91_RS11205 (2181275) 2181275..2182591 - 1317 WP_004399369.1 hypothetical protein -
K6J91_RS11210 (2182948) 2182948..2183454 - 507 WP_004399486.1 hypothetical protein -
K6J91_RS11215 (2183782) 2183782..2185014 - 1233 WP_004399445.1 hypothetical protein -
K6J91_RS11220 (2185096) 2185096..2185284 - 189 WP_004399547.1 hypothetical protein -
K6J91_RS11225 (2185329) 2185329..2185580 - 252 WP_010886546.1 hypothetical protein -
K6J91_RS11230 (2185599) 2185599..2185775 - 177 WP_009967515.1 hypothetical protein Toxin
- (2185716) 2185716..2185816 + 101 NuclAT_2 - Antitoxin
- (2185716) 2185716..2185816 + 101 NuclAT_2 - Antitoxin
- (2185716) 2185716..2185816 + 101 NuclAT_2 - Antitoxin
- (2185716) 2185716..2185816 + 101 NuclAT_2 - Antitoxin
K6J91_RS11235 (2186150) 2186150..2186761 - 612 WP_009967516.1 lipoprotein -
K6J91_RS11240 (2186876) 2186876..2187202 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6J91_RS11245 (2188155) 2188155..2188349 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2117443..2266470 149027


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T39041 WP_009967515.1 NZ_AP024624:c2185775-2185599 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T39041 NZ_AP024624:c2185775-2185599 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT39041 NZ_AP024624:2185716-2185816 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References