Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
| Location | 1638324..1638614 | Replicon | chromosome |
| Accession | NZ_CP120681 | ||
| Organism | Bacillus subtilis strain DSM 10 | ||
Toxin (Protein)
| Gene name | bsrG | Uniprot ID | L8EAY0 |
| Locus tag | P5655_RS08885 | Protein ID | WP_009967548.1 |
| Coordinates | 1638324..1638440 (+) | Length | 39 a.a. |
Antitoxin (RNA)
| Gene name | as-bsrH | ||
| Locus tag | - | ||
| Coordinates | 1638435..1638614 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P5655_RS08850 (1634251) | 1634251..1634421 | - | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
| P5655_RS08855 (1634718) | 1634718..1635035 | - | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
| P5655_RS08860 (1635137) | 1635137..1636387 | - | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
| P5655_RS08865 (1636380) | 1636380..1636712 | - | 333 | WP_004398710.1 | YolD-like family protein | - |
| P5655_RS08870 (1636886) | 1636886..1637221 | + | 336 | WP_004399073.1 | hypothetical protein | - |
| P5655_RS08875 (1637264) | 1637264..1637620 | - | 357 | WP_004398595.1 | hypothetical protein | - |
| P5655_RS08880 (1637626) | 1637626..1638093 | - | 468 | WP_003246138.1 | YolA family protein | - |
| P5655_RS08885 (1638324) | 1638324..1638440 | + | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
| - (1638435) | 1638435..1638614 | - | 180 | NuclAT_1 | - | Antitoxin |
| - (1638435) | 1638435..1638614 | - | 180 | NuclAT_1 | - | Antitoxin |
| - (1638435) | 1638435..1638614 | - | 180 | NuclAT_1 | - | Antitoxin |
| - (1638435) | 1638435..1638614 | - | 180 | NuclAT_1 | - | Antitoxin |
| P5655_RS08890 (1638719) | 1638719..1639252 | - | 534 | WP_004399156.1 | GNAT family protein | - |
| P5655_RS08895 (1639288) | 1639288..1639866 | - | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
| P5655_RS08900 (1639930) | 1639930..1640427 | - | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
| P5655_RS08905 (1640436) | 1640436..1642151 | - | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
| P5655_RS08910 (1642251) | 1642251..1642808 | - | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
| P5655_RS08915 (1642943) | 1642943..1643077 | + | 135 | WP_234047931.1 | transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 1516355..1665384 | 149029 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T275361 WP_009967548.1 NZ_CP120681:1638324-1638440 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
Antitoxin
Download Length: 180 bp
>AT275361 NZ_CP120681:c1638614-1638435 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
