Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2392206..2392423 Replicon chromosome
Accession NZ_CP015375
Organism Bacillus subtilis subsp. subtilis strain KCTC 3135

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag AS891_RS12705 Protein ID WP_009967515.1
Coordinates 2392247..2392423 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2392206..2392306 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS891_RS12690 2389673..2389867 - 195 WP_004399291.1 hypothetical protein -
AS891_RS12695 2390820..2391146 + 327 WP_009967517.1 helix-turn-helix domain-containing protein -
AS891_RS12700 2391261..2391872 + 612 WP_009967516.1 lipoprotein -
- 2392206..2392306 - 101 NuclAT_2 - Antitoxin
- 2392206..2392306 - 101 NuclAT_2 - Antitoxin
- 2392206..2392306 - 101 NuclAT_2 - Antitoxin
- 2392206..2392306 - 101 NuclAT_2 - Antitoxin
AS891_RS12705 2392247..2392423 + 177 WP_009967515.1 hypothetical protein Toxin
AS891_RS22505 2392442..2392693 + 252 WP_010886546.1 hypothetical protein -
AS891_RS12710 2392738..2392926 + 189 WP_004399547.1 hypothetical protein -
AS891_RS12715 2393008..2394240 + 1233 WP_004399445.1 hypothetical protein -
AS891_RS12720 2394568..2395074 + 507 WP_004399486.1 hypothetical protein -
AS891_RS12725 2395431..2396747 + 1317 WP_004399369.1 hypothetical protein -
AS891_RS12730 2397008..2397235 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2325154..2460581 135427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T62922 WP_009967515.1 NZ_CP015375:2392247-2392423 [Bacillus subtilis subsp. subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T62922 NZ_CP015375:2392247-2392423 [Bacillus subtilis subsp. subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT62922 NZ_CP015375:c2392306-2392206 [Bacillus subtilis subsp. subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References